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ALL MEDICAL CODES IN CATEGORY Genomic Sequencing Procedures (GSP)
2025 CPT code 0246U
Red blood cell antigen typing using DNA genotyping for at least 16 blood groups, predicting at least 51 red blood cell antigens.
2025 CPT code 0186U
This CPT code reports the Navigator FUT2 Sequencing test, analyzing FUT2 gene exon 2 to determine H blood group antigen status, aiding in minimizing blood type incompatibility risks.
This CPT code reports genotyping for Gerbich blood group (GE) antigens by analyzing exons 1-4 of the GYPC gene.
2025 CPT code +0073U
CYP2D6 gene analysis, targeted sequence analysis (CYP2D7-2D6 hybrid gene), performed as a follow-up test when initial testing does not determine the patient's CYP2D6 genotype.
2025 CPT code 0027U
JAK2 Exons 12-15 Sequencing (JAKXR) analysis; a proprietary algorithm distinguishes myeloproliferative neoplasm polycythemia vera from other erythrocytoses.
2025 CPT code 0235U
Genomic Unity® PTEN Analysis; evaluates the PTEN gene for variants relevant to conditions like hamartoma tumor syndrome.
2025 CPT code 0233U
Genomic Unity® FXN Analysis evaluates the frataxin (FXN) gene for variants related to conditions like Friedreich's ataxia using WGS.
2025 CPT code 0425U
Rapid whole genome sequencing analysis of a comparator genome (e.g., parent or sibling) to identify genetic variants in a symptomatic patient.
2025 CPT code 0426U
Ultra-rapid whole genome sequencing analysis to identify genetic variants for diagnosing or ruling out genetic diseases in newborns or symptomatic children.
2025 CPT code 0215U
Analysis of a comparator's exome and mitochondrial DNA to identify genetic variants, aiding in diagnosing constitutional or genetic disorders.
2025 CPT code 0350U
Analysis of 27 genes related to drug metabolism and processing, using a whole blood or buccal swab specimen and next-generation sequencing.
2025 CPT code 0217U
Genomic DNA sequence analysis of 51 genes associated with ataxia, including small sequence changes, deletions, duplications, short tandem repeat gene expansions, and variants in non-uniquely mappable regions from blood or saliva samples.
2025 CPT code +0071U
CYP2D6 gene analysis, full gene sequence; add-on code.
2025 CPT code 0218U
This code reports Genomic Unity® DMD Analysis from Variantyx Inc., a test analyzing the DMD gene for muscular dystrophy, including full gene sequencing and duplication/deletion analysis.
2025 CPT code 0355U
Apolipoprotein L1 (APOL1) Renal Risk Variant Genotyping, a proprietary test from Quest Diagnostics, analyzes a blood or saliva sample to detect G1 and G2 variants in the APOL1 gene, aiding in kidney transplant donor/recipient risk assessment.
2025 CPT code 0222U
Red blood cell antigen (Rh blood group) genotyping using next-generation sequencing (NGS).
2025 CPT code 0237U
Genomic sequence analysis panel for cardiac ion channelopathies, including 10 genes, using PCR-free whole genome sequencing.
2025 CPT code 0070U
CYP2D6 Common Variants and Copy Number test, identifying variants impacting medication metabolism.
2025 CPT code 0030U
Targeted sequence analysis for warfarin drug response, assessing CYP2C9, CYP4F2, VKORC1, and rs12777823 genes.
2025 CPT code 0234U
Genomic Unity® MECP2 Analysis from Variantyx Inc., using PCR-free whole genome sequencing (WGS) to evaluate the MECP2 gene for variants.
2025 CPT code 0216U
Genomic DNA sequence analysis of 12 common genes associated with inherited ataxias, identifying small sequence changes, deletions, duplications, short tandem repeat expansions, and variants in non-uniquely mappable regions from blood or saliva samples.
2025 CPT code 0200U
This CPT code reports the Navigator XK Sequencing test by Grifols Immunohematology Center, analyzing exons 1-3 of the XK gene to determine Kx blood group antigens.
2025 CPT code 0379U
Targeted genomic sequence analysis panel for solid organ neoplasms, analyzing DNA (523 genes) and RNA (55 genes) via next-generation sequencing (NGS) to identify sequence variants, gene copy number amplifications, rearrangements, microsatellite instability, and tumor mutational burden.
2025 CPT code 0236U
Analysis of SMN1 and SMN2 genes using genomic sequencing to detect variants associated with conditions like spinal muscular atrophy.
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