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2025 CPT code 96416

Initiation of a prolonged chemotherapy infusion (more than 8 hours) using a portable or implantable pump.

Chemotherapy administration into the peritoneal cavity via an implanted port or catheter.

This add-on code reports each additional hour of intra-arterial chemotherapy infusion, beyond the initial hour (96422).

Irrigation of implanted venous access device for drug delivery systems.

Chemotherapy administration into pleural cavity, requiring and including thoracentesis.

Chemotherapy administration; intralesional, more than 7 lesions.

Chemotherapy injection, subarachnoid or intraventricular via subcutaneous reservoir, single or multiple agents.

Chemotherapy administration; intravenous push technique, single or initial substance/drug.

Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug.

Chemotherapy administration, intra-arterial infusion, initiation of prolonged infusion (more than 8 hours) using a portable or implantable pump.

Chemotherapy administration, intra-arterial; infusion technique, up to 1 hour.

Refilling and maintenance of an implantable pump or reservoir for systemic drug delivery.