iFrame.AI – Discover What Matters

ALL MEDICAL CODES IN CATEGORY Molecular Pathology Procedures

2025 CPT code 81273

KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (eg, mastocytosis), gene analysis, D816 variant(s).

2025 CPT code 81258

HBA1/HBA2 (alpha globin 1 and alpha globin 2) gene analysis for known familial variants.

2025 CPT code 81163

BRCA1 and BRCA2 gene analysis; full sequence analysis.

2025 CPT code 81217

BRCA2 (BRCA2, DNA repair associated) (eg, hereditary breast and ovarian cancer) gene analysis; known familial variant

2025 CPT code 81255

HEXA (hexosaminidase A [alpha polypeptide]) (eg, Tay-Sachs disease) gene analysis, common variants (eg, 1278insTATC, 1421+1G>C, G269S).

2025 CPT code 81269

Analysis of HBA1/HBA2 genes for duplications and deletions, associated with alpha thalassemia.

2025 CPT code 81327

This CPT code represents the analysis of Septin9 (SEPT9) gene promoter methylation, typically using a blood sample, to detect methylation patterns that may indicate colorectal cancer.

2025 CPT code 81342

Analysis of T-cell receptor gamma (TRG) gene rearrangements to detect abnormal clonal T-cell populations, which may indicate leukemia or lymphoma.

2025 CPT code 81381

High-resolution HLA Class I typing for a single allele or allele group.

2025 CPT code 81112

Analysis of the common alleles of Human Platelet Antigen 15 (HPA-15), also known as CD109 (CD109 molecule), using a blood or amniotic fluid specimen.

2025 CPT code 81370

HLA Class I and II typing, low resolution, molecular techniques.

2025 CPT code 81109

Analysis of common Human Platelet Antigen 5 (HPA-5) gene variants (e.g., HPA-5a/b [K505E]) using a patient specimen (e.g., blood).

2025 CPT code 81332

Analysis of common SERPINA1 gene variants (e.g., *S and *Z) associated with alpha-1-antitrypsin deficiency.

2025 CPT code 81345

Analysis of the telomerase reverse transcriptase (TERT) gene, focusing on targeted sequences like the promoter region.

2025 CPT code 81216

Analysis of the complete BRCA2 gene sequence.

2025 CPT code 81352

Targeted sequence analysis of the TP53 gene.

2025 CPT code 81279

Targeted sequence analysis of the JAK2 (Janus kinase 2) gene, focusing on exons 12 and 13, often used in myeloproliferative neoplasm (MPN) diagnostics.

2025 CPT code 81307

Analysis of the entire PALB2 gene sequence; detects variants associated with breast and pancreatic cancer risk.

2025 CPT code 81176

Analysis of a targeted gene sequence, such as exon 12, for ASXL1 (additional sex combs like 1, transcriptional regulator).

2025 CPT code 81252

Analysis of the complete GJB2 gene sequence, encompassing all exons and introns, to identify variations associated with hearing loss.

2025 CPT code 81212

Analysis of BRCA1 and BRCA2 genes for common variants (185delAG, 5385insC, 6174delT).

2025 CPT code 81265

Comparative analysis using Short Tandem Repeat (STR) markers; patient and comparative specimen (e.g., pre-transplant recipient and donor germline testing, post-transplant non-hematopoietic recipient germline [e.g., buccal swab or other germline tissue sample] and donor testing, twin zygosity testing, or maternal cell contamination of fetal cells).

2025 CPT code 81323

PTEN (phosphatase and tensin homolog) (eg, Cowden syndrome, PTEN hamartoma tumor syndrome) gene analysis; duplication/deletion variant

2025 CPT code 81331

Methylation analysis of SNRPN and UBE3A genes (e.g., for Prader-Willi and/or Angelman syndromes).

2025 CPT code 81232

Analysis of common variants in the dihydropyrimidine dehydrogenase (DPYD) gene (e.g., *2A, *4, *5, *6) to assess drug metabolism, primarily for 5-fluorouracil (5-FU) and capecitabine.

2025 CPT code 81246

Analysis of FLT3 gene for tyrosine kinase domain (TKD) variants.

2025 CPT code 81361

Analysis of the HBB gene for common variants (e.g., HbS, HbC, HbE).

2025 CPT code 81194

Analysis of NTRK1, NTRK2, and NTRK3 gene translocations.

2025 CPT code 81178

Analysis of the ATXN1 gene to detect abnormal alleles, specifically expanded sequences, often associated with spinocerebellar ataxia type 1 (SCA1).

2025 CPT code 81208

Analysis of BCR/ABL1 gene sequences at breakpoints other than major or minor, qualitative or quantitative.

2025 CPT code 81259

Full gene sequence analysis of HBA1/HBA2 genes (alpha globin 1 and alpha globin 2) related to alpha thalassemia and some hemoglobinopathies.

2025 CPT code 81164

BRCA1 and BRCA2 gene analysis; full duplication/deletion analysis.

2025 CPT code 81183

Analysis of the ATXN10 gene to detect abnormal alleles, particularly expanded sequences.

2025 CPT code 81257

Analysis of HBA1/HBA2 genes (alpha globin 1 and 2) for common deletions or variants associated with alpha thalassemia and other hemoglobinopathies.

2025 CPT code 81242

Analysis of the FANCC gene for common variants, such as IVS4+4A>T, associated with Fanconi anemia.

2025 CPT code 81317

Analysis of the entire PMS2 gene sequence.

2025 CPT code 81204

Analysis of the androgen receptor (AR) gene to characterize alleles, such as expanded size or methylation status.

2025 CPT code 81291

Analysis of common variants in the MTHFR gene.

2025 CPT code 81108

This code represents Human Platelet Antigen 4 (HPA-4) genotyping, analyzing common variants HPA-4a/b (R143Q) in the ITGB3 gene.The test aids in diagnosing conditions such as neonatal alloimmune thrombocytopenia (NAIT).

2025 CPT code 81248

Analysis of known familial variants in the glucose-6-phosphate dehydrogenase (G6PD) gene.

2025 CPT code 81231

Analysis of common CYP3A5 gene variants (*2, *3, *4, *5, *6, *7) impacting drug metabolism.

2025 CPT code 81229

Cytogenomic (genome-wide) microarray analysis for constitutional chromosomal abnormalities; interrogation of genomic regions for copy number and single nucleotide polymorphism (SNP) variants.

2025 CPT code 81355

Analysis of VKORC1 gene for common variants related to warfarin metabolism.

2025 CPT code 81210

BRAF (B-Raf proto-oncogene, serine/threonine kinase) gene analysis for V600 variant(s).

2025 CPT code 81383

HLA Class II typing, high resolution (ie, alleles or allele groups); one allele or allele group (eg, HLA-DQB1*06:02P), each

2025 CPT code 81121

IDH2 (isocitrate dehydrogenase 2 [NADP+], mitochondrial) (eg, glioma), common variants (eg, R140W, R172M).

2025 CPT code 81377

HLA Class II typing, low resolution (e.g., antigen equivalents); one antigen equivalent, each.

2025 CPT code 81272

KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (e.g., gastrointestinal stromal tumor [GIST], acute myeloid leukemia, melanoma), gene analysis, targeted sequence analysis (e.g., exons 8, 11, 13, 17, 18).

2025 CPT code 81238

F9 (coagulation factor IX) (eg, hemophilia B), full gene sequence

2025 CPT code 81230

Analysis of the CYP3A4 gene for common variants (e.g., *2, *22) to assess drug metabolism.

Enterprise Edition

Upgrade for detailed insurance, legislation, and other documents analytics for individual cases; real-time analysis of the datasets from your EHR, CRM, ERP, or other software; and more Enterprise Features.