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ALL MEDICAL CODES IN CATEGORY Multianalyte assays with algorithmic analyses (MAAA)

2025 CPT code 0092U

REVEAL Lung Nodule Characterization test; analyzes three protein biomarkers in blood plasma to assess lung nodule malignancy risk.

2025 CPT code 0390U

This CPT code reports a serum biomarker test (PEPredictDx) to assess preeclampsia risk in pregnant women using immunoassay and an algorithm to generate a risk score.

2025 CPT code 0320U

Post-kidney transplant blood test using next-generation sequencing to assess the risk of acute cellular rejection.

2025 CPT code 0095U

Analysis of eotaxin-3 and major basic protein via ELISA, specimen from esophageal string test, algorithm reports probability of active eosinophilic esophagitis.

2025 CPT code 0421U

This code represents a fecal-based colorectal cancer screening test that analyzes the expression of eight genes and fecal hemoglobin, providing a positive or negative risk assessment for colorectal cancer.

2025 CPT code 0319U

Pre-kidney transplant testing using next-generation sequencing (NGS) of specific parts of the transcriptome to evaluate gene expression related to immune response, resulting in a risk score for early acute rejection.

2025 CPT code 0332U

Genetic profiling of 8 epigenetic markers using qPCR on a whole blood sample, assessing the likelihood of response to immune checkpoint inhibitor therapy in cancer patients.

2025 CPT code 0312U

Analysis of 8 IgG autoantibodies and 2 cell-bound complement activation products for autoimmune diseases (e.g., SLE), using ELISA, flow cytometry, and immunofluorescence; individual components reported with an algorithmic SLE-likelihood assessment.

2025 CPT code 0365U

Oncuria® Detect test for bladder cancer probability using urine immunoassay and algorithmic analysis of 10 protein biomarkers.

2025 CPT code 0088U

Kidney transplant rejection assessment via microarray gene expression profiling of 1494 genes; algorithm provides a rejection probability score.

2025 CPT code 0309U

Analysis of four proteins (NT-proBNP, osteopontin, TIMP-1, and KIM-1) in a plasma specimen; algorithm reported as a risk score for major adverse cardiovascular events.

2025 CPT code 0117U

Pain management; analysis of 11 endogenous urinary analytes by LC-MS/MS; algorithm reported as a pain-index score.

2025 CPT code 0122U

Measures the adhesion of whole blood to P-selectin, assessing the effects of drugs in preventing cell adhesion in sickle cell disease patients.

2025 CPT code 0389U

This CPT code reports a specific proprietary laboratory analysis (PLA) for Kawasaki disease risk assessment using RNA expression of two genes (IFI27 and MCEMP1) via RT-qPCR.

2025 CPT code 0366U

Analysis of 10 protein biomarkers (A1AT, ANG, APOE, CA9, IL8, MMP9, MMP10, PAI1, SDC1, and VEGFA) in urine via immunoassay; algorithm determines probability of recurrent bladder cancer.

2025 CPT code 0437U

This CPT code reports the MindX One™ Blood Test — Anxiety, a proprietary laboratory analysis (PLA) using gene expression profiling of 15 genes to provide a predictive risk score for anxiety disorders.