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ALL MEDICAL CODES IN CATEGORY Pathology and Laboratory Procedures > Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

2025 CPT code 81415

Exome (e.g., unexplained constitutional or heritable disorder or syndrome); sequence analysis

2025 CPT code 81456

Genomic sequence analysis panel evaluating RNA alterations in 51 or more genes related to solid organ or hematolymphoid cancers.

2025 CPT code 81471

Analyzes a patient specimen for duplication and deletion mutations in at least 60 genes, including 15 genes related to X-linked intellectual disability (XLID).

2025 CPT code 81459

Genomic sequence analysis panel for solid organ neoplasm; DNA/RNA analysis for sequence variants, copy number variants, rearrangements, MSI, and TMB.

2025 CPT code 81418

This code represents a genomic sequence analysis panel for drug metabolism (pharmacogenomics) that includes at least six genes, notably CYP2C19 and CYP2D6, with CYP2D6 duplication/deletion analysis.

2025 CPT code 81463

Genomic sequence analysis panel of cell-free DNA (cfDNA) in plasma, evaluating sequence variants, copy number variants, and microsatellite instability (MSI) for solid organ neoplasms.

2025 CPT code 81445

Genomic sequence analysis panel for solid organ neoplasm; 5-50 genes; DNA or combined DNA/RNA analysis.

2025 CPT code 81410

Genomic sequence analysis panel for aortic dysfunction or dilation, including at least 9 genes (FBN1, TGFBR1, TGFBR2, COL3A1, MYH11, ACTA2, SLC2A10, SMAD3, MYLK).

2025 CPT code 81450

Genomic sequence analysis panel for hematolymphoid neoplasms; DNA or combined DNA/RNA analysis.

2025 CPT code 81420

Genomic sequence analysis panel for fetal chromosomal aneuploidy using circulating cell-free fetal DNA in maternal blood; includes chromosomes 13, 18, and 21.

2025 CPT code 81427

Re-evaluation of a patient's previously obtained whole genome sequence analysis, considering new information like updated knowledge or a different condition.

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