ALL MEDICAL CODES IN CATEGORY Pathology and Laboratory Procedures > Molecular Pathology Procedures

2025 CPT code 81254

GJB6 (gap junction protein, beta 6, 30kDa, connexin 30) (e.g., nonsyndromic hearing loss) gene analysis, common variants (e.g., 309kb [del(GJB6-D13S1830)] and 232kb [del(GJB6-D13S1854)])

2025 CPT code 81249

G6PD (glucose-6-phosphate dehydrogenase) (eg, hemolytic anemia, jaundice), gene analysis; full gene sequence

2025 CPT code 81313

PCA3/KLK3(prostate cancer antigen 3 [non-protein coding]/kallikrein-related peptidase 3 [prostate specific antigen]) ratio (eg, prostate cancer)

2025 CPT code 81202

Analysis of known familial variants in the adenomatous polyposis coli (APC) gene.

2025 CPT code 81304

MECP2 (methyl CpG binding protein 2) (eg, Rett syndrome) gene analysis; duplication/deletion variants

2025 CPT code 81308

PALB2 (partner and localizer of BRCA2) (eg, breast and pancreatic cancer) gene analysis; known familial variant

2025 CPT code 81325

PMP22 (peripheral myelin protein 22) (eg, Charcot-Marie-Tooth, hereditary neuropathy with liability to pressure palsies) gene analysis; full sequence analysis

2025 CPT code 81277

Cytogenomic (genome-wide) microarray analysis for neoplasia; interrogation of genomic regions for copy number and loss-of-heterozygosity variants for chromosomal abnormalities.

2025 CPT code 81344

TBP (TATA box binding protein) (eg, spinocerebellar ataxia) gene analysis, evaluation to detect abnormal (eg, expanded) alleles

2025 CPT code 81175

ASXL1(additional sex combs like 1, transcriptional regulator) (eg, myelodysplastic syndrome, myeloproliferative neoplasms, chronic myelomonocytic leukemia), gene analysis; full gene sequence

2025 CPT code 81250

G6PC (glucose-6-phosphatase, catalytic subunit) (eg, Glycogen storage disease, Type 1a, von Gierke disease) gene analysis, common variants (eg, R83C, Q347X).

2025 CPT code 81241

F5 (coagulation Factor V) (eg, hereditary hypercoagulability) gene analysis, Leiden variant

2025 CPT code 81293

MLH1(mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; known familial variants

2025 CPT code 81289

FXN(frataxin) (eg, Friedreich ataxia) gene analysis; known familial variant(s)

2025 CPT code 81335

TPMT (thiopurine S-methyltransferase) (e.g., drug metabolism), gene analysis, common variants (e.g., *2, *3)

2025 CPT code 81374

HLA Class I typing, low resolution (eg, antigen equivalents); one antigen equivalent (eg, B*27), each