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2025 CPT code 44376

Small intestinal endoscopy, enteroscopy beyond the second portion of the duodenum, including the ileum; diagnostic, with or without collection of specimen(s) by brushing or washing (separate procedure).

Refer to CPT coding guidelines for specific instructions on coding enteroscopy procedures.

Modifiers may be applicable.Refer to current CPT guidelines for proper modifier usage.

Medical necessity is established by the clinical indication for the procedure. The documentation should support the need for the enteroscopy to evaluate a specific symptom, finding, or condition.

The physician performs the enteroscopy, inserting the endoscope, visualizing the small intestine, and collecting any necessary specimens.

IMPORTANT:Do not report 44376 in conjunction with 44360, 44361, 44363, 44364, 44365, 44366, 44369, 44370, 44372, 44373.

In simple words: The doctor uses a thin, flexible tube with a camera and light to look inside your small intestine, all the way to the end. They might also take small samples to test.

This procedure involves a visual examination of the small intestine using a fiberoptic endoscope that goes beyond the second part of the duodenum and includes the ileum. It is done for diagnostic purposes and may also include collecting tissue samples by brushing or washing the lining of the intestine.

Example 1: A patient presents with chronic abdominal pain and unexplained weight loss. An enteroscopy is performed to examine the small intestine for abnormalities like Crohn's disease or tumors., During an upper endoscopy, a suspicious area is found in the duodenum. A deep enteroscopy (44376) is performed to further examine and biopsy the area., A patient has obscure gastrointestinal bleeding. An enteroscopy is performed to locate the source of bleeding in the small intestine.

Documentation should include the indication for the procedure, the extent of the examination (specifically noting that the ileum was reached), any procedures performed (e.g., biopsy, brushings), and findings.

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