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2025 CPT code 46606

Anoscopy with biopsy, single or multiple.

Refer to the current CPT manual for detailed coding guidelines.

Modifiers may be applicable depending on the circumstances of the procedure (e.g., 22 for increased procedural services, 51 for multiple procedures, 59 for distinct procedural service). Consult the CPT guidelines for appropriate modifier usage.

Medical necessity for anoscopy with biopsy is established by symptoms such as rectal bleeding, anal pain, or abnormal findings on digital rectal examination, warranting further investigation to identify the underlying cause.

The physician inserts the anoscope, visualizes the anal canal and rectum, and obtains tissue samples using biopsy forceps.Appropriate patient preparation and anesthesia are also the responsibility of the physician.

IMPORTANT:For high-resolution anoscopy with biopsy, use 46607.Do not report 46600 in conjunction with 46020-46947, 0184T, during the same operative session.

In simple words: The doctor uses a thin, lighted tube to examine the inside of your anus and rectum.They may take small tissue samples for testing.

Anoscopy is a procedure where a small, rigid, tubular instrument (anoscope) is inserted into the anal canal to visually examine the anus and rectum.A biopsy involves removing tissue samples from the anal lining for pathological examination. This CPT code encompasses both the anoscopy and the collection of single or multiple tissue samples for biopsy.

Example 1: A patient presents with rectal bleeding. Anoscopy with biopsy is performed to identify the cause of the bleeding, such as hemorrhoids, polyps, or cancer., A patient has abnormal findings on a digital rectal exam. Anoscopy with biopsy is performed to further evaluate the findings and obtain tissue samples for analysis., A patient presents with anal discomfort and itching.Anoscopy with biopsy is performed to rule out anal fissures, infections, or other pathologies.

* Operative report detailing the procedure, including the number of biopsies taken.* Pathology report detailing the results of the biopsy.* Preoperative and postoperative notes documenting patient condition.* Medical necessity documentation explaining the reason for the procedure based on symptoms and findings.

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