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BETA v.3.0

2025 CPT code 51727

Complex cystometrogram (i.e., calibrated electronic equipment); with urethral pressure profile studies (i.e., urethral closure pressure profile), any technique.

When multiple procedures from the range 51725-51798 are performed in the same session, modifier 51 should be used. If the physician only interprets the results and/or operates the equipment, modifier 26 should be used.

Modifiers 22, 26, 51, among others may be applicable.

Medical necessity must be established for this procedure. The documentation should clearly demonstrate the clinical rationale for performing the complex cystometrogram with urethral pressure profile studies, linking the test to the patient's symptoms and suspected diagnosis.The documentation should also explain why less invasive diagnostic methods were insufficient.

Performed by or under the direct supervision of a physician or other qualified healthcare professional.Includes provision of all instruments, equipment, fluids, etc.

In simple words: This test helps diagnose urinary problems by measuring the pressure in your bladder and urethra. A small tube is inserted into the bladder to fill it with water, and the pressure is recorded. Another measurement is taken in the urethra to see if you leak urine when you cough, which can indicate stress incontinence.

This procedure involves a complex cystometrogram, utilizing calibrated electronic equipment, along with urethral pressure profile studies (specifically urethral closure pressure profile) using any technique.A complex cystometrogram measures bladder pressure during filling with sterile water through a transurethral catheter while simultaneously monitoring rectal pressure using a manometer.This helps determine the presence of spontaneous bladder contractions (spasms). The urethral pressure profile study measures the pressure required to keep the urethra closed by withdrawing the catheter into the urethra and asking the patient to cough, thus assessing for stress incontinence (urine leakage).

Example 1: A 55-year-old female presents with symptoms of stress urinary incontinence, experiencing leakage with coughing and sneezing. A complex cystometrogram with urethral pressure profile studies is performed to assess bladder function and urethral closure pressure during stress maneuvers., A 60-year-old male with a history of benign prostatic hyperplasia presents with difficulty voiding and a weak urinary stream. A complex cystometrogram with urethral pressure profile studies is performed to evaluate for bladder outlet obstruction and assess urethral function., A 40-year-old female experiences urinary urgency and frequency, suggestive of overactive bladder. A complex cystometrogram with urethral pressure profile studies is performed to assess bladder storage function and rule out other causes of her symptoms.

Documentation should include the type of cystometrogram performed (complex), the use of calibrated electronic equipment, the performance of urethral pressure profile studies including urethral closure pressure measurements, the technique used, the patient's symptoms, and the interpretation of the study results. Any associated diagnoses, such as stress incontinence or overactive bladder, should also be documented.

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