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2025 CPT code 61546

Craniotomy for hypophysectomy or pituitary tumor excision via intracranial approach.

Consult the official AMA CPT coding guidelines for neurosurgical procedures for detailed instructions and clarifications.

Modifiers may be applicable based on specific circumstances of the procedure, such as multiple procedures (modifier 51), increased procedural services (modifier 22), or other relevant modifiers. Consult the CPT manual for more guidance.

The procedure is medically necessary for patients with pituitary adenomas causing hormonal imbalances (e.g., Cushing's disease, acromegaly), visual field deficits, or other significant symptoms.Hypophysectomy may be indicated for certain non-tumorous conditions.

The neurosurgeon is responsible for all aspects of the procedure, including the craniotomy, pituitary gland access, tumor resection or hypophysectomy, hemostasis (control of bleeding), wound closure, and post-operative care instructions.

IMPORTANT 61548 (Hypophysectomy or excision of pituitary tumor, transnasal or transseptal approach, nonstereotactic) may be used for alternative approaches.

In simple words: The doctor opens the skull to remove the pituitary gland (hypophysectomy) or a tumor on the pituitary gland.After the procedure, the skull is closed.

This procedure involves a craniotomy, an intracranial surgical approach to the pituitary gland, for either hypophysectomy (removal of the pituitary gland) or excision (surgical removal) of a pituitary tumor.The neurosurgeon removes a portion of the skull bone to access the pituitary gland, performs the necessary resection or excision, addresses any bleeding or fluid accumulation, and then reconstructs the skull using plates, wires, or sutures, and applies a sterile dressing.

Example 1: A patient presents with a large pituitary adenoma causing significant visual field deficits.A craniotomy is performed for excision of the tumor., A patient with Cushing's disease due to a pituitary adenoma undergoes a hypophysectomy via a craniotomy., A patient with acromegaly resulting from a growth hormone-secreting pituitary adenoma has a craniotomy with tumor resection.

** Use of an operating microscope is not separately billable with this code according to Medicare guidelines.The choice between 61546 and 61548 depends on the surgical approach.

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