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2025 CPT code 64483

Transforaminal epidural injection of anesthetic and/or steroid with imaging guidance (fluoroscopy or CT) at a single lumbar or sacral level.

For bilateral procedures, append modifier 50.Do not report imaging guidance separately.For each additional level injected at the same interspace, use 64484.

Modifiers such as 50 (bilateral procedure), 73 (discontinued procedure prior to anesthesia), 74 (discontinued procedure after anesthesia), etc. may be applicable depending on the circumstances.

Medical necessity for this procedure is established by documentation of the patient's pain, functional limitations, and failed conservative treatment options. Supporting documentation such as imaging studies (MRI, CT) confirming the diagnosis may also be required.

A physician specializing in pain management or anesthesiology typically performs this procedure.

IMPORTANT:For additional levels, use add-on code 64484.For cervical/thoracic transforaminal epidural injections, see codes 64479 and 64480.

In simple words: This procedure helps relieve lower back pain or sciatica by injecting medicine around a specific nerve in your lower back.A special x-ray or CT scan is used to make sure the medicine reaches the right spot.

This code describes a procedure where an anesthetic agent and/or steroid is injected into the transforaminal epidural space at a single level in either the lumbar or sacral region. Imaging guidance, using either fluoroscopy or CT, is an integral part of the procedure and is included in this code.The injection targets a specific nerve root.

Example 1: A patient with lumbar radiculopathy at L5 experiences severe leg pain. A transforaminal epidural injection at L5 is performed under fluoroscopic guidance to relieve the pain and inflammation., A patient with a herniated disc at S1 has persistent sciatica.A transforaminal epidural injection at S1 is performed with CT guidance to target the affected nerve root., A patient with lower back pain radiating to the leg undergoes a transforaminal epidural injection at the affected lumbar level using fluoroscopy to deliver medication directly to the source of the pain. Modifier -50 is applied as the procedure is bilateral.

Documentation should include the diagnosis, the specific level of injection (e.g., L4-L5), the type of imaging guidance used (fluoroscopy or CT), the medications injected, and the patient's response to the procedure. The medical necessity of the procedure must also be documented.

** Check with individual payers for specific coverage policies and documentation requirements. The average patient payment in 2024 for this code in an Ambulatory Surgical Center setting is about $115. This is just an average and the actual cost may vary.

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