In simple words: This procedure uses a radioactive solution to kill cancer cells. The solution is either put directly on the cancer or injected into a vein.The treatment includes a hospital stay and check-ups for three months after.

This CPT code encompasses the infusion or instillation of a radioelement solution for the purpose of destroying cancerous cells.The procedure includes hospital admission and three months of post-procedure follow-up care.The radioelement solution may be instilled directly onto tumor cells (e.g., in pleural or peritoneal cavity tumors) or infused intravenously (e.g., for bone cancers). This method is also known as unsealed internal radiation therapy.

Example 1: A patient with pleural effusion secondary to lung cancer undergoes instillation of a radioelement solution into the pleural space to reduce tumor burden and alleviate symptoms., A patient with metastatic bone cancer receives intravenous infusion of a radioelement solution to target and destroy cancerous cells throughout the skeletal system., A patient with peritoneal carcinomatosis receives intraperitoneal instillation of a radioelement solution to target cancerous cells in the abdominal cavity.

* Complete medical history including diagnosis and staging of cancer.* Detailed description of the procedure performed, including type and amount of radioelement solution used, method of administration, and location of administration.* Documentation of patient's response to treatment, including any adverse events.* Evidence of medical necessity, including clinical indications for using this form of radiation therapy.* Relevant imaging studies (e.g., CT, MRI, PET) before and after the procedure.* Follow-up notes demonstrating the 3-month post-procedure care.

** The cost of the radiopharmaceutical may be billed separately using the appropriate HCPCS code.Pay close attention to payer-specific policies regarding modifier usage and global surgical packages.