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2025 CPT code 77778

Interstitial radiation source application; complex; includes supervision, handling, and loading of the radiation source when performed.

Refer to the American College of Radiology (ACR) and the American Brachytherapy Society (ABS) guidelines for appropriate selection and use of interstitial brachytherapy procedures.

Modifiers 26 (professional component) and TC (technical component) can be applied as appropriate based on the services rendered.Modifier 52 (reduced services) may be used in certain circumstances, such as when only a portion of the planned procedure is performed.

Medical necessity for 77778 is established by the presence of a malignant tumor suitable for interstitial brachytherapy. The treatment must be medically appropriate for the patient's disease, and the expected benefits should outweigh the potential risks.The procedure should align with established guidelines, including tumor type, stage, and location.The benefits of brachytherapy over other options should be documented.

The therapeutic radiologist is responsible for the supervision of radioelements, dose interpretation, and the overall management of the brachytherapy procedure.This includes pre-treatment planning, implantation of the radioactive sources, post-implantation monitoring, and follow-up care.Additional responsibilities may include image guidance and managing any complications.

IMPORTANT:Do not report 77778 with Category III codes 0394T, 0395T or with 77790. For insertion of ovoids and tandems, use 57155. For insertion of Heyman capsules, use 58346. For treatment by injectable or ingestible isotopes, see Nuclear Medicine codes.

In simple words: This procedure uses tiny radioactive implants to treat a tumor. The doctor places more than 10 of these implants directly into the tumor using thin tubes or needles. This is a complex treatment requiring specialized training.

This CPT code 77778 describes the complex application of interstitial radiation sources.It involves the placement of more than 10 radioactive sources directly into a tumor using catheters or needles. The procedure includes the supervision, handling, and loading of the radiation source, when performed.This is a high-level procedure requiring specialized knowledge and skills in radiation oncology.

Example 1: A patient with a locally advanced cervical cancer undergoes interstitial brachytherapy using 77778. More than 10 radioactive seeds are implanted into the tumor under image guidance (fluoroscopy or CT).The procedure requires specialized applicators and meticulous placement of sources. Post-implantation imaging is done to verify correct seed placement. The patient's radiation dose is carefully monitored and managed. , A patient diagnosed with prostate cancer receives interstitial brachytherapy for high-risk disease. A complex implant is placed using more than 10 radioactive seeds via transperineal approach.The procedure is performed with the help of real-time imaging guidance to optimize seed placement.The patient is monitored for side effects and compliance with treatment plan.The radiologist actively manages the treatment based on the outcome of various imaging and lab tests during the course of therapy., A patient with recurrent breast cancer receives a complex interstitial brachytherapy implant using more than 10 radioactive sources, targeting the tumor bed.This procedure is performed to reduce the risk of recurrence, and the radioactive seeds are strategically positioned based on preoperative imaging and surgical findings. The patient needs regular follow-up to monitor for adverse effects, such as skin reactions or fibrosis. The radiologist manages the treatment based on response to therapy and any adverse effects.

* Detailed treatment plan outlining the number and type of radioactive sources, their placement, and the total dose administered.* Pre-procedure imaging studies (e.g., CT, MRI) to delineate the target volume and surrounding tissues.* Intra-operative images (fluoroscopy or CT) documenting the placement of radioactive sources.* Post-procedure images to verify source placement and evaluate the dose distribution.* Patient's medical history and any relevant comorbidities.* Informed consent document signed by the patient.* Detailed record of the source handling, loading, and disposal procedures.

** This code is for complex interstitial brachytherapy procedures only.For simple or intermediate procedures, use other appropriate CPT codes.Always refer to the latest CPT codebook and payer-specific guidelines for accurate billing and reimbursement.

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