2025 CPT code 80349
(Active) Effective Date: N/A Revision Date: N/A Laboratory - Drug Assay Procedures Pathology and Laboratory Procedures Feed
Qualitative or quantitative analysis of natural cannabinoids in a patient specimen.
Modifiers 59 (distinct procedural service) and 90 (reference laboratory) might be applicable in certain circumstances.
Medical necessity will depend on the clinical indication.Examples include suspicion of cannabinoid overdose, monitoring patient compliance with treatment regimens, and forensic investigations. Supporting documentation should justify the medical necessity based on the specific clinical scenario.
A laboratory analyst performs the test, measuring or detecting natural cannabinoids in a patient sample.The ordering physician interprets results in the context of patient history and clinical presentation.
In simple words: This lab test checks for natural cannabinoids (chemicals found in the cannabis plant) in a sample from your body (like urine). The test can tell you if these substances are present and how much is there.
This CPT code encompasses the qualitative or quantitative analysis of natural cannabinoids present in a patient's specimen.The testing method may involve techniques such as high-performance gas chromatography (HPGC) or other definitive methods capable of distinguishing between structural isomers.Results can be reported as qualitative (positive/negative) or quantitative (measured amount). Various specimen types may be used, including but not limited to urine, blood, oral fluid, meconium, or hair.The analysis may include cannabinoid metabolites if they are specifically listed in the Definitive Drug Classes Listing.
Example 1: A patient presents with suspected cannabinoid overdose. A quantitative 80349 is ordered to determine the concentration of cannabinoids in their blood., A patient is on a court-ordered drug monitoring program.A qualitative 80349 urine test is performed to screen for natural cannabinoids. , A research study requires the analysis of cannabinoids in hair samples to assess long-term use patterns. Multiple 80349 tests with modifier 59 are reported if testing on multiple specimen types.
* Patient demographics and identification information.* Physician's order specifying the test (80349) and specimen type(s).* Date and time of specimen collection.* Complete laboratory report including methodology, results (qualitative and/or quantitative), and interpretation.
** Always cross-reference with the current CPT manual, NCCI edits, and payer-specific guidelines for accurate billing and reimbursement.
- Revenue Code: T1H (LAB TESTS - OTHER (NON-MEDICARE FEE SCHEDULE))
- RVU: Information not available in provided text. Consult current fee schedules and RVU databases for accurate values.
- Global Days: Not applicable to laboratory tests.
- Payment Status: Active
- Modifier TC rule: Not applicable.
- Fee Schedule: Information not available in the provided text. Consult historical CPT fee schedules for relevant data.
- Specialties:Toxicology, addiction medicine, emergency medicine, occupational medicine, forensic medicine.
- Place of Service:Office, Hospital (Inpatient/Outpatient), Laboratory, Urgent Care Facility, other.