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BETA v.3.0

2025 CPT code 82040

Albumin; serum, plasma or whole blood.

Do not report 82040 if the albumin test is part of a comprehensive metabolic panel, renal function panel, or hepatic function panel, as it is included in those panels. Modifier QW should be appended if the test is performed in a CLIA-waived facility.

Modifier 91 is used for repeat laboratory tests. Modifier QW is used for CLIA waived tests. Other modifiers such as 59, 90, 99 can be applicable as well

Medical necessity for this test depends on the patient's clinical presentation and suspected condition. It is typically justified when there is a need to evaluate liver function, nutritional status, or kidney function. Additionally it is useful for assessing hydration levels.

Lab analysts perform this test using methods like spectrophotometry or nephelometry. It's an important part of assessing a patient's overall health and diagnosing certain medical conditions.

In simple words: This test measures the amount of albumin in your blood. Albumin is a protein made by your liver, and this test helps doctors check for problems with your liver or kidneys, or if you're not getting enough nutrients.

Quantitative measurement of albumin in serum, plasma, or whole blood. This test is commonly performed using spectrophotometry or nephelometry and plays a crucial role in assessing various conditions, including dehydration, malnutrition, and liver function.

Example 1: A patient presents with symptoms of dehydration and malnutrition. The physician orders an albumin test (82040) to assess the patient's nutritional status and level of hydration. , A patient with a history of liver disease undergoes regular albumin testing (82040) to monitor liver function and detect any signs of deterioration., A patient experiencing swelling and fluid retention is tested for albumin (82040) to evaluate kidney function and identify potential causes of the fluid imbalance.

Documentation should include the source of the specimen (serum, plasma, or whole blood), the date and time of collection, and the reason for the test. Any relevant clinical findings or symptoms should also be documented.

** Albumin is a key protein in the blood and helps maintain osmotic pressure, transport substances, and assess nutritional status and liver function. Its measurement aids in diagnosing and monitoring several health conditions. The test should not be reported separately when performed as part of certain panels.

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