2025 CPT code 82106
(Active) Effective Date: N/A Revision Date: N/A Laboratory - Chemistry Procedures Pathology and Laboratory Procedures Feed
Alpha-fetoprotein (AFP) quantitative measurement in amniotic fluid.
Modifiers 90 (Reference (Outside) Laboratory) and 91 (Repeat Clinical Diagnostic Laboratory Test) might apply depending on circumstances.
Medical necessity for this test is established when a physician orders it to screen for potential fetal abnormalities or monitor high-risk pregnancies based on clinical indications (e.g., maternal age, family history, ultrasound findings).
The clinical responsibility lies with the laboratory analyst who performs the quantitative measurement of AFP in the amniotic fluid sample using an immunoassay method.
In simple words: This lab test measures the amount of alpha-fetoprotein (AFP) in amniotic fluid (the fluid surrounding a baby in the womb).The test is usually done between weeks 11 and 15 of pregnancy and helps check for potential problems with the baby's development.
This CPT code, 82106, represents the quantitative measurement of alpha-fetoprotein (AFP) in amniotic fluid.The test is typically performed on a sample obtained between the 11th and 15th week of gestation.The procedure involves using an immunoassay method to determine the AFP concentration. AFP is a protein produced by the fetal liver and yolk sac, and its levels in amniotic fluid can be indicative of certain fetal abnormalities. The result is a quantitative value representing the concentration of AFP in the amniotic fluid sample.
Example 1: A pregnant woman at 13 weeks gestation undergoes amniocentesis.The amniotic fluid is sent to the lab for AFP testing to screen for neural tube defects., A high-risk pregnancy is being monitored, and serial AFP levels are ordered in amniotic fluid to track fetal development and potential abnormalities., As part of a comprehensive prenatal screening, AFP levels are assessed in amniotic fluid to aid in risk stratification for various fetal conditions.
* Patient demographics and identification.* Physician's order specifying the test (82106).* Date and time of amniocentesis.* Gestational age at the time of sampling.* Volume of amniotic fluid collected.* Proper labeling and handling of the sample.* Complete laboratory report including quantitative AFP results and reference ranges.
** The abbreviation AFP-AF may be used for this test.Results should be interpreted in conjunction with other clinical data and appropriate gestational age references.
- Revenue Code: T1H (LAB TESTS - OTHER (NON-MEDICARE FEE SCHEDULE))
- Payment Status: Active
- Specialties:Obstetrics, Gynecology, Maternal-Fetal Medicine
- Place of Service:Laboratory