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BETA v.3.0

2025 CPT code 82248

Laboratory test to measure the amount of direct bilirubin in a patient's blood.

When a direct bilirubin test is performed along with a total bilirubin test, both codes (82247 for total bilirubin and 82248 for direct bilirubin) may be reported separately. If other liver function tests are performed, ensure appropriate coding guidelines are followed for each test.

Modifiers may be applicable. Modifier 91 is used for repeat laboratory tests on the same day. Modifier 90 indicates that the test was performed by an outside laboratory.

Medical necessity for this test is established by the presence of signs or symptoms suggestive of liver dysfunction, such as jaundice, abdominal pain, nausea, or fatigue. It can also be used for monitoring known liver conditions.

The laboratory analyst performs the direct bilirubin test on a blood specimen. The test may involve colorimetric analysis, where a color reagent is added to the specimen, and the color intensity is measured to determine the bilirubin concentration. Clinicians use this test to evaluate liver health in patients with symptoms of abnormal liver function, often in conjunction with other tests for liver enzymes.

In simple words: This blood test measures the level of direct bilirubin, a substance produced when your body breaks down old red blood cells. It helps doctors check how well your liver is working and can help diagnose liver or bile duct problems.

This test measures conjugated (direct) bilirubin in the blood. Direct bilirubin is a form of bilirubin that has been processed by the liver and is water-soluble. This test is used to evaluate liver function and diagnose conditions affecting the liver or bile ducts.

Example 1: A patient presents with jaundice, yellowing of the skin and eyes, prompting the physician to order a direct bilirubin test to assess liver function and diagnose potential underlying conditions such as hepatitis or bile duct obstruction., A newborn with jaundice undergoes a direct bilirubin test to assess the severity of the condition and guide treatment decisions. Elevated levels in newborns can lead to serious complications if not addressed., A patient with a history of liver disease has routine direct bilirubin testing to monitor liver function and disease progression, alongside other liver function tests. This allows for adjustments to treatment plans if necessary.

Proper documentation for billing this code includes the patient's medical history, the reason for the test, the date and time of sample collection, the method of analysis, and the test results.

** The test should be protected from light as bilirubin is light-sensitive. Different laboratories may have slightly different normal ranges for direct bilirubin levels. Results should be interpreted in conjunction with the patient's clinical picture and other laboratory findings.

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