2025 CPT code 82397
(Active) Effective Date: N/A Revision Date: N/A Laboratory - Chemiluminescent Assay Pathology and Laboratory Procedures > Chemistry Procedures Feed
Chemiluminescent assay; a laboratory test that measures the quantity of an analyte by mixing chemicals with a specimen, causing luminescence.
Modifiers may apply depending on the specific circumstances of the test (e.g., 90 for reference laboratory, 91 for repeat testing). Consult the CPT manual and payer guidelines for appropriate modifier use.
Medical necessity is determined by the ordering physician based on the patient's clinical presentation, symptoms, and other diagnostic findings. The chemiluminescent assay should be ordered when a rapid, highly sensitive method is required for quantitative measurement of a specific analyte.
The lab analyst performs all technical steps, such as mixing the patient’s specimen with chemicals. The resulting reaction causes some substances to produce light. The lab analyst then measures the analyte on a special machine.
In simple words: This lab test measures the amount of a specific substance in your sample (like blood or urine) by making it glow. The glow's brightness tells the doctor how much of the substance is present. It's a very sensitive test, and it can be used for many different things.
The chemiluminescent assay is a laboratory test used to quantitatively measure an analyte in a specimen.The procedure involves mixing the specimen with chemicals, causing the analyte to become luminescent (to glow). The intensity of the luminescence is directly proportional to the concentration of the analyte, and is measured using a luminometer. This assay is considered more sensitive than colorimetric methods. The test is applicable to a wide variety of substances and is not limited to testing for a specific condition.The specific analyte being measured must be identified separately.
Example 1: A patient presents with suspected hormone imbalances. A chemiluminescent assay is used to measure hormone levels in a blood sample to aid in diagnosis., A patient has a suspected infection. A chemiluminescent assay is performed on a blood sample to detect and quantify specific inflammatory markers., A patient undergoes a cardiac enzyme test following a suspected myocardial infarction. A chemiluminescent assay is used for fast and sensitive detection of troponin levels in the blood.
* Patient demographics and identifiers.* Ordering physician information.* Date and time of specimen collection.* Specimen type (e.g., serum, plasma, urine).* Specific analyte(s) being tested.* Test results and interpretation.* Any relevant clinical information.
** The chemiluminescent assay is a highly sensitive method utilized for a broad spectrum of analytes.Always specify the analyte being measured in the claim submission.Consider potential additional codes for specimen collection if separately performed.
- Revenue Code: T1H
- RVU: Information not available in provided text. Refer to CMS guidelines for current RVU values.
- Global Days : Not applicable. This is a laboratory test, not a surgical procedure.
- Payment Status: Active
- Modifier TC rule: Not applicable. This code refers to the complete laboratory test procedure.
- Fee Schedule : Information not available in the provided text.Consult payer-specific fee schedules and historical data sources.
- Specialties:* Clinical Chemistry* Endocrinology* Cardiology* Infectious Disease* Immunology* Oncology
- Place of Service:Office, Hospital (Inpatient/Outpatient), Laboratory, Ambulatory Surgical Center