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2025 CPT code 82672

Measures the total level of estrogens in serum or urine samples, providing an overall assessment of estrogen status in both males and females.

Follow current CPT coding guidelines for laboratory services.Specific guidelines regarding specimen collection, handling, and reporting are crucial for accurate billing.

Modifiers may be applicable depending on the circumstances of service. Consult appropriate modifier guidelines for specific scenarios (e.g., modifier 90 for outside lab testing).

Medical necessity is established based on the clinical indication for testing. This could include evaluating symptoms suggestive of hormonal imbalances, monitoring the effectiveness of hormone replacement therapies, or investigating potential endocrine disorders.

The clinical responsibility lies with the laboratory analyst who performs the quantitative analysis of total estrogens.The ordering physician interprets the results within the context of the patient's clinical presentation and other relevant findings.

IMPORTANT:For individual estrogen fractions: 82670 (estradiol), 82677 (estriol), 82679 (estrone). For multiple estrogen fractions: 82671.If measuring estrogen receptor, use code 84233.

In simple words: This lab test measures the total amount of estrogen hormones in a blood or urine sample.It gives a general idea of how much estrogen is present in a person's body, which can be useful for various health reasons. This test doesn't measure the amount of each individual type of estrogen.

This CPT code (82672) encompasses the laboratory analysis to quantitatively determine the total estrogen levels in serum or urine specimens obtained from male or female patients.The assay measures the combined concentration of various estrogens, including estradiol, estriol, estrone, and estetrol (produced by the fetal liver during pregnancy).Common methodologies employed include enzyme-linked immunosorbent assays (ELISA) and radioimmunoassays (RIA).The results provide a comprehensive overview of an individual's estrogen status and are used clinically in various situations, such as evaluating hypogonadism, assessing ovarian function, detecting estrogen-producing tumors, monitoring estrogen replacement therapies, and evaluating feminization in males. The test does not differentiate between individual estrogen types.

Example 1: A 45-year-old woman presents with symptoms suggestive of menopause.Total estrogen levels are ordered to assess ovarian function and guide hormone replacement therapy., A 28-year-old woman is undergoing infertility treatment. Total estrogen levels are monitored to determine the optimal timing for ovulation and conception., A 60-year-old male patient presents with gynecomastia (breast enlargement). Total estrogen levels are measured to investigate potential hormonal imbalances or estrogen-producing tumors.

* Patient demographics and relevant medical history.* Reason for ordering the test (e.g., suspected hormonal imbalance, infertility evaluation, tumor investigation).* Date and time of specimen collection.* Type of specimen (serum or urine).* Laboratory report with quantitative results, reference ranges, and any relevant comments.

** Accurate interpretation of total estrogen levels requires consideration of the patient's age, sex, and clinical context.Results should be interpreted in conjunction with other relevant clinical information.

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