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2025 CPT code 82785

Measures the total serum IgE level in a specimen.

Adhere to all CPT coding guidelines regarding laboratory testing.Ensure proper documentation supporting the medical necessity of the test.Modifiers may apply depending on the setting and circumstances of the service.

Modifiers may be applicable depending on the context of service provision (e.g., modifier 90 for outside lab, 91 for repeat testing). Consult appropriate guidelines for modifier usage.

Medical necessity for this test depends on the clinical context. It's usually not appropriate for general allergy screening.The test may be medically necessary to evaluate patients with suspected hyper-IgE syndrome, allergic bronchopulmonary aspergillosis (ABPA), other immunodeficiencies or patients with unexplained symptoms suggesting an immune dysfunction related to elevated IgE levels. Supporting clinical documentation is required for proper justification.

The clinical responsibility lies primarily with the laboratory personnel who perform the test and interpret the results. The ordering physician is responsible for determining the medical necessity for the test and integrating the results into the patient's overall care.

IMPORTANT:For allergen-specific IgE testing, refer to codes 86003 and 86005.This test is not typically appropriate for general allergy testing; other codes may be more suitable in those cases.

In simple words: This lab test measures the amount of immunoglobulin E (IgE) in your blood. IgE is a type of antibody related to allergies. High IgE levels may indicate an allergic condition or other health problems.The test helps your doctor understand your body's response to allergens or infections.

This CPT code reports the quantitative measurement of total serum Immunoglobulin E (IgE) levels.The test involves a laboratory procedure to analyze a patient specimen (e.g., plasma or serum) for IgE concentration.The methodology may involve techniques such as immunofluorescence or ELISA.Results are expressed as a numerical value reflecting the IgE concentration. This test is not typically used for general allergy screening but may be indicated in specific clinical situations such as monitoring patients with suspected immunodeficiencies or certain allergic conditions, such as allergic bronchopulmonary aspergillosis (ABPA) or hyper-IgE syndrome.

Example 1: A patient presents with recurrent respiratory infections and a history of eczema.The physician orders this test to assess for hyper-IgE syndrome., A patient diagnosed with allergic bronchopulmonary aspergillosis (ABPA) requires regular monitoring of their IgE levels. This test is ordered to track disease progression and response to treatment., A patient with chronic hives and suspected mast cell activation disorder undergoes this test as part of a comprehensive evaluation to identify the underlying cause.

Complete patient demographics, detailed clinical history including symptoms, relevant prior tests, and the reason for ordering the IgE test.The lab report should include the measured IgE level and units.

** Consider payer-specific guidelines and LCDs related to allergy testing before billing this code, as it is often deemed inappropriate for general allergy screening.Many payers may require additional documentation to support medical necessity.

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