2025 CPT code 84431
(Active) Effective Date: N/A Pathology and Laboratory Procedures - Chemistry Procedures Pathology and Laboratory Feed
Thromboxane metabolite(s), including thromboxane if performed, urine.
Modifiers may be applicable. Modifier 90 is used if the test is performed by a reference (outside) laboratory. Modifier 91 is used if the test is a repeat clinical diagnostic laboratory test.
Medical necessity for this test should be documented based on the individual patient's clinical presentation, signs, and symptoms, along with the physician's assessment of risk factors for thrombotic events. If the test is used to monitor aspirin therapy, the documentation should reflect this intent.
The lab analyst performs the technical lab steps to mix patient urine with specific substances to measure one or more thromboxane metabolites, including thromboxane if the analyst tests for it.
In simple words: This test measures substances related to thromboxane, a chemical in your blood that helps clotting, in your urine. It can help doctors see if you're at risk for blood clots or if your aspirin is working effectively.
This test measures thromboxane metabolites, including thromboxane if performed, in urine.Thromboxane is an enzyme found in platelets that assists in clot formation and constricts blood vessels. The metabolites are thromboxane A2 and thromboxane B2. The test may involve methods such as mass spectrometry. Although not limited to testing for a specific condition, this test is typically ordered to evaluate patients for increased risk of blood clots or stroke, or to check for decreased levels to evaluate the effectiveness of aspirin therapy.
Example 1: A patient is experiencing symptoms of a stroke and the physician orders this test to assess thromboxane levels to help determine the potential presence of a blood clot., A patient is on aspirin therapy to reduce their risk of blood clots. The physician orders this test to monitor the effectiveness of the aspirin therapy, as aspirin inhibits thromboxane production., A patient with a family history of blood clots undergoes this test as part of a risk assessment for potential clotting disorders.
The documentation should include the reason for the test, the patient's relevant medical history (including any medications such as aspirin), the date and time of urine collection, and the method used for analysis.
** For concurrent urine creatinine determination, use 84431 in conjunction with 82570.Clinical information or mathematically calculated values derived from other tests are not separately reportable.
- Revenue Code: T1H
- Specialties:Pathology, Hematology, Cardiology
- Place of Service:Independent Laboratory, Hospital Laboratory