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2025 CPT code 84446

This CPT code reports the laboratory analysis of alpha-tocopherol (vitamin E) levels, typically in serum or plasma.

Follow current CPT coding guidelines and payer-specific rules. Refer to the AMA's CPT manual for complete guidelines and instructions.

Modifiers may be applicable depending on the circumstances of service, such as the place of service or the type of laboratory test performed. Refer to the AMA's CPT manual and payer's specific guidelines for applicable modifiers.

Medical necessity is established when there is a clinical indication for evaluating vitamin E levels. This could include assessing risk factors for deficiency, evaluating symptoms suggestive of deficiency, or monitoring the effectiveness of vitamin E replacement therapy. The medical necessity justification should be clearly documented in the patient's medical record.

The clinical responsibility lies with the laboratory analyst who performs the technical aspects of the test, including specimen handling, analysis, and result reporting. The ordering physician interprets the results in the context of the patient's clinical presentation.

IMPORTANT No alternate codes explicitly listed.However, depending on the specific test methodology or clinical context, other related CPT codes may be applicable.

In simple words: This lab test measures the amount of vitamin E in your blood.Vitamin E is an antioxidant that protects your cells. This test can help find out if you have a vitamin E deficiency or to check how well vitamin E treatment is working.

CPT code 84446 represents the analytical procedure for measuring alpha-tocopherol (vitamin E) concentration.The specimen is usually serum or plasma. The methodology may involve techniques like chromatography. This test helps assess vitamin E deficiency, monitor vitamin E therapy (especially in premature infants receiving oxygen), and evaluate conditions related to antioxidant status and its impact on vascular and nervous system health.

Example 1: A pediatrician orders an alpha-tocopherol level for an infant born prematurely who is receiving supplemental oxygen due to respiratory distress syndrome.This helps monitor for vitamin E deficiency, a known complication in this population., A gastroenterologist orders this test for a patient presenting with signs and symptoms of malabsorption, including neurological symptoms suggestive of vitamin E deficiency., A neurologist is assessing a patient for peripheral neuropathy.Alpha-tocopherol levels are checked as part of a broader metabolic panel to investigate the possibility of vitamin E deficiency as a contributing factor.

* Physician order specifying the test (alpha-tocopherol level).* Patient demographics and identification information.* Details on specimen collection (date, time, type of specimen).* Complete and accurate laboratory report including the result, reference range, and any relevant comments or observations.* Documentation of the clinical indication for ordering the test (reason for suspecting vitamin E deficiency or need to monitor therapy).

** Specific methodologies for alpha-tocopherol measurement may vary among laboratories.Results should be interpreted in the context of the patient's clinical presentation and other relevant laboratory findings.Always refer to laboratory-specific reference ranges.

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