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2025 CPT code 84591

Vitamin assay, not otherwise specified.

Follow CPT guidelines for laboratory and pathology coding.Use the most specific code available.When multiple analytes are measured, report each separately.

Modifiers may be applicable depending on the circumstances of service. Consult the CPT manual for specific modifier guidelines.Modifiers such as 90 (reference laboratory) and 91 (repeat test) may apply.

Medical necessity is established when there is clinical suspicion of a specific vitamin deficiency based on the patient's history, physical examination, and other clinical findings.Medicare generally does not cover vitamin assays as screening tests unless there is a documented specific clinical need.

Laboratory personnel perform the technical aspects of the analysis.Physicians are responsible for ordering the test, interpreting the results, and implementing appropriate treatment plans.

IMPORTANT Use more specific CPT codes if available for the particular vitamin being tested.If multiple vitamins are tested, individual codes should be reported for each vitamin where possible.For panels, refer to codes 80048-80076.

In simple words: This lab test measures the amount of a vitamin in your blood or urine to check for a deficiency.It's used when there isn't a more specific test for that particular vitamin.

This CPT code, 84591, reports the analysis of a vitamin level in a patient specimen (blood or urine) when no more specific CPT code exists for the vitamin in question.The analysis is quantitative unless otherwise specified. This code is used only for vitamins lacking a more specific code; examples include vitamins B3 and B7.The clinical utility of this code is primarily in identifying deficiencies requiring dietary changes or supplementation.

Example 1: A patient presents with symptoms suggestive of biotin deficiency.A physician orders a vitamin B7 (biotin) assay using code 84591 because no specific CPT code for biotin exists in that specific testing methodology., A patient with unexplained neurological symptoms undergoes a panel of vitamin assays.One of the vitamins tested, for which a specific code is unavailable, is reported using 84591., A patient with suspected nutritional deficiencies is tested for multiple vitamins.Vitamin B3 analysis is reported using 84591, as no separate, more specific CPT code is applicable.

Physician's order specifying the vitamin(s) to be tested.Patient demographics.Specimen type (blood or urine).Results of the test.Any relevant clinical information supporting medical necessity.

** This code should be used judiciously.Always use a more specific CPT code if one exists for the vitamin being tested.Proper documentation is crucial for demonstrating medical necessity, especially for Medicare reimbursement.

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