2025 CPT code 85576
(Deleted) Effective Date: N/A Revision Date: N/A Deletion Date: N/A Pathology and Laboratory Procedures - Platelet function testing Hematology and Coagulation Procedures Feed
Platelet aggregation (in vitro), each agent.
Modifier 26 (professional component) may be applicable if the pathologist interprets and reports the results.
Medical necessity for this test is established by the presence of clinical symptoms or conditions suggestive of platelet dysfunction (e.g., unexplained bleeding, easy bruising, prolonged bleeding times) or the need to monitor the effects of medication on platelet aggregation.
The clinical responsibility lies with the laboratory analyst who performs the technical aspects of the test, including specimen preparation, reagent addition, and analysis using specialized instrumentation to measure platelet aggregation. The pathologist may be responsible for interpretation and report generation, depending on lab protocols and clinician requests.
In simple words: This lab test checks how well your platelets clump together to help your blood clot.A special chemical is added to a blood sample to see how much clumping occurs. This helps doctors figure out why you might have bleeding problems.
This CPT code reports the in-vitro testing of platelet aggregation using a single reagent.The test involves adding a specific reagent (e.g., epinephrine, collagen, ristocetin, ADP, thrombin, arachidonic acid) to a blood sample and measuring the degree of platelet clumping. This helps assess platelet function and may be used in the diagnosis of bleeding disorders or platelet dysfunction. Each reagent tested is reported separately.
Example 1: A patient presents with easy bruising and prolonged bleeding after minor injuries.The physician orders platelet aggregation studies with multiple reagents (e.g., collagen, ADP, epinephrine) to evaluate for potential platelet dysfunction. Each reagent used would be billed separately using code 85576 (now deleted)., A patient with a known history of von Willebrand's disease undergoes routine monitoring of platelet function. Platelet aggregation testing with ristocetin is performed to assess von Willebrand factor activity. This would have been reported with code 85576 (now deleted)., A patient on aspirin therapy experiences unexpected bleeding. Platelet aggregation testing with multiple agents (including ADP and collagen) is performed to assess the impact of aspirin on platelet function.Each reagent would have been billed separately using code 85576 (now deleted).
* Patient demographics and relevant clinical history.* Indication for testing (e.g., suspected bleeding disorder, medication effects).* List of reagents used for each test performed.* Detailed results of each platelet aggregation test, including graphs or quantitative measurements.* Pathologist's interpretation and report (if applicable).
** Code 85576 is a deleted CPT code.Clinicians should refer to current CPT guidelines for appropriate replacement codes when billing for platelet aggregation testing. The information provided reflects the historical context of this code.
- Revenue Code: T1H (LAB TESTS - OTHER (NON-MEDICARE FEE SCHEDULE))
- Payment Status: Inactive
- Modifier TC rule: The technical component (TC) is usually included in the basic code; however, modifier 26 may be used for the professional component if the pathologist provides interpretation and reporting.
- Specialties:Hematology, Pathology, Thrombosis
- Place of Service:Hospital laboratory, Clinical laboratory