Start New EnglishEspañol中文РусскийالعربيةTiếng ViệtFrançaisDeutsch한국어Tagalog Library Performance
BETA v.3.0

2025 CPT code 87426

Infectious agent antigen detection by immunoassay; severe acute respiratory syndrome coronavirus (SARS-CoV, SARS-CoV-2 [COVID-19]).

Follow current CPT coding guidelines for laboratory procedures. Consult the American Medical Association (AMA) CPT manual for the most up-to-date information.

Modifiers such as 90 (reference laboratory) or 91 (repeat test) may apply depending on the specific circumstances.

Medical necessity for this test is established when the physician orders it to diagnose or rule out COVID-19 infection, for pre-operative screening in high-risk situations, or for monitoring healthcare workers with potential exposure.

The clinical responsibility lies with the laboratory analyst who performs the immunoassay, interprets the results, and reports them to the ordering physician. The ordering physician is responsible for integrating the results into the patient's overall care.

IMPORTANT:For SARS-CoV-2 DNA or RNA nucleic acid detection by amplified probe technique, see 87635.For single-step immunoassay using a reagent strip (point-of-care testing for SARS-CoV-2 antibodies), see 86328. For multiple-step immunoassay using a reagent strip (point-of-care testing for SARS-CoV-2 antibodies), see 86769. HCPCS Level II codes for laboratory testing for SARS-CoV-2 include U0001 (CDC-developed kit) and U0002 (tests developed by other labs).Specimen collection may be separately coded (e.g., 36415).

In simple words: This lab test checks a blood sample for the presence of the virus that causes COVID-19.The test uses a special method to detect parts of the virus.

This CPT code represents the qualitative or semiquantitative detection of severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-2, which causes COVID-19) antigens in a patient specimen using an immunoassay technique.Immunoassay techniques may include enzyme immunoassay (EIA), enzyme-linked immunosorbent assay (ELISA), fluorescence immunoassay (FIA), or immunochemiluminometric assay (IMCA). The test evaluates the presence and/or concentration of the viral antigen.

Example 1: A patient presents with symptoms consistent with COVID-19 (fever, cough, shortness of breath).The physician orders this test to confirm the diagnosis., A patient requires pre-operative testing before a scheduled surgery.The physician orders this test as part of routine pre-operative screening., A healthcare worker is exposed to a patient with confirmed COVID-19.This test is ordered to monitor for infection.

Complete patient demographics, date of service, specimen type (e.g., nasal swab, blood), test result (qualitative or semi-quantitative), and physician's order.

** This code may be used in conjunction with other codes for complete billing.Payers may have specific requirements for reimbursement.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

Discover what matters.

iFrame™ AI's knowledge is aligned with and limited to the materials uploaded by users and should not be interpreted as medical, legal, or any other form of advice by iFrame™.