Start New EnglishEspañol中文РусскийالعربيةTiếng ViệtFrançaisDeutsch한국어Tagalog Library Performance
BETA v.3.0

2025 CPT code 87652

Infectious agent detection by nucleic acid (DNA or RNA); Streptococcus, group A, quantification

For multiple specimens/sites use modifier 59. For repeat laboratory tests performed on the same day, use modifier 91. Do not use molecular diagnostic codes (e.g., 81161, 81200-81408) in combination with or instead of 87140-87158 if additional molecular studies are performed.

Modifiers 59 and 91 are applicable as described in the coding guidelines.

Medical necessity for this test is established when a patient exhibits signs and symptoms of a Streptococcus, group A, infection, and quantification of the bacteria is needed to guide treatment decisions or monitor treatment efficacy.

The lab analyst processes the specimen, performs amplification techniques like PCR, and then uses a nucleic acid probe to quantify the Streptococcus, group A, microorganisms present.

In simple words: This test measures the amount of Group A Strep bacteria in a sample, like a throat swab, using a DNA/RNA-based method. It helps determine how much of the bacteria is present, giving a more precise measure of the infection level.

This code represents a laboratory test that quantifies Streptococcus, group A, infection using a nucleic acid probe technique. The process involves amplifying the target nucleic acid sequence (often through PCR), then using a labeled nucleic acid probe to hybridize with the amplified sequences, enabling visualization and quantification of the Streptococcus, group A, microorganisms present in the specimen.

Example 1: A patient presents with a severe sore throat, and the physician orders this test to quantify the Group A Strep infection to guide antibiotic treatment., A patient with recurrent strep throat infections undergoes this test to assess the bacterial load and monitor treatment effectiveness., A public health official uses this test during an outbreak investigation to quantify the severity of Streptococcus, group A, infections in the affected population.

Documentation should include the source of the specimen (e.g., throat swab), the reason for testing (e.g., symptoms), and the interpretation of the quantitative results.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

Discover what matters.

iFrame™ AI's knowledge is aligned with and limited to the materials uploaded by users and should not be interpreted as medical, legal, or any other form of advice by iFrame™.