In simple words: This test analyzes the genetic makeup of the hepatitis B virus in a patient's sample to see if it has changed in ways that make it resistant to treatment.

This code represents the laboratory analysis of a specimen to determine the genotype of the Hepatitis B virus using nucleic acid testing (DNA or RNA).The process may involve techniques like polymerase chain reaction (PCR) to amplify the viral nucleic acid, followed by sequencing to identify specific genetic markers. This information helps determine if the virus has mutated, especially concerning drug resistance.

Example 1: A patient being treated for chronic hepatitis B is not responding to antiviral therapy.The physician orders this test to check for drug resistance mutations in the virus., A patient newly diagnosed with hepatitis B is having this test done to determine the specific genotype of the virus, which can inform treatment decisions and prognosis., A patient with a history of hepatitis B needs antiviral treatment and the test helps in making informed decision for further treatment.

Documentation should include the physician's order for the test, the reason for testing (e.g., suspected drug resistance, initial genotyping), the date the specimen was collected, the type of specimen, and the laboratory's report including the genotype identified.