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2025 CPT code 88143

Cytopathology; cervical or vaginal specimen in preservative fluid, automated thin layer preparation; manual screening and rescreening under physician supervision.

Adhere to CPT guidelines, specifically those related to cytopathology procedures.Accurate documentation is essential for appropriate code selection.The choice between 88143 and other similar codes depends on the specific methodologies used by the laboratory.

Modifiers may be applicable depending on the circumstances of service, such as the place of service or the nature of the screening (e.g., preventive versus diagnostic). Consult current CPT modifier guidelines.

Medical necessity for this test is established based on the patient's age, risk factors (family history of cervical cancer, prior abnormal Pap smears), and clinical presentation (vaginal bleeding, discharge, etc.).Screening guidelines vary; compliance with those guidelines is crucial for medical necessity determination.

The clinical responsibility lies with the laboratory analyst for the technical aspects of the test (specimen preparation, screening, and rescreening) under the supervision of a physician (usually a pathologist) who interprets the results.

IMPORTANT:For automated screening of automated thin layer preparation, see 88174 and 88175.Other codes (88142, 88147, 88148, 88164-88167, 88174-88175) may apply depending on the specific method used.

In simple words: This lab test examines cells from the cervix or vagina.The sample is prepared using a special machine, then checked twice under a microscope by a lab technician to look for abnormalities.A doctor oversees the process.

This CPT code, 88143, represents the technical component of a cytopathology procedure involving a cervical or vaginal specimen. The specimen is collected in preservative fluid and processed using automated thin layer preparation.The procedure includes manual microscopic screening and rescreening of the prepared slides by a laboratory analyst under physician supervision.The reporting system used (e.g., Bethesda or other) is not specified in the code itself.This code reflects two manual screenings conducted by the analyst.

Example 1: Annual well-woman exam including Pap smear., Follow-up Pap smear after an abnormal result from a previous test., Patient presents with vaginal bleeding or discharge; Pap smear ordered to rule out malignancy.

* Patient demographics and relevant history.* Detailed description of the specimen collection method.* Confirmation of the use of preservative fluid and automated thin layer preparation.* Documentation of the two manual screenings performed by the analyst, noting any discrepancies or findings.* Physician's interpretation of the results and any subsequent diagnostic or therapeutic steps.

** This code is specifically for manual screening and rescreening; automated systems should use other applicable CPT codes.Always refer to the most up-to-date CPT manual and payer guidelines for accurate billing and coding practices.

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