2025 CPT code 88166
(Active) Effective Date: N/A Pathology and Laboratory Procedures - Cytopathology Pathology and Laboratory Feed
Cytopathology, slides, cervical or vaginal (the Bethesda System); with manual screening and computer-assisted rescreening under physician supervision.
Medical necessity for this code depends on the patient’s symptoms, risk factors, and clinical presentation. Routine screening, follow-up of abnormal findings, and evaluation of specific symptoms can justify the use of this code.
The lab analyst performs the technical aspects of the procedure, including manual and computer-assisted screening. A physician supervises the process and interprets the results.
In simple words: This test analyzes cells collected from the cervix or vagina (like a Pap smear) to check for abnormalities. A lab technician first examines the cells under a microscope and then uses a computer program to double-check the results. The results are reported using a standardized system called the Bethesda System.
This code represents a cytopathology procedure for cervical or vaginal slides using the Bethesda System reporting method. It involves an initial manual screening of the slide followed by a computer-assisted rescreening, all performed under the supervision of a physician.This is typically used when the initial manual screening identifies an abnormality requiring further evaluation with computer assistance.
Example 1: A patient undergoes a routine Pap smear as part of an annual exam. The initial manual screening shows atypical cells. The slide is then rescreened using computer assistance to confirm the findings., A patient experiences vaginal bleeding and undergoes a Pap smear. The initial manual screening is inconclusive.A computer-assisted rescreening is performed to aid in the diagnosis., A patient with a family history of cervical cancer undergoes a Pap smear. The manual screening shows some abnormal cells, and the computer-assisted rescreening helps determine the severity of the abnormality.
Documentation should include the type of specimen collected, the method of preparation, the results of both manual and computer-assisted screenings, and the interpretation using the Bethesda System terminology.
** It is important to differentiate this code from other Pap smear codes based on the specific method of screening and reporting used.
- Specialties:Pathology, Obstetrics and Gynecology, Family Medicine
- Place of Service:Office, Outpatient Hospital, Independent Laboratory