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BETA v.3.0

2025 CPT code 89280

Assisted oocyte fertilization, microtechnique; less than or equal to 10 oocytes.

Report 89280 for assisted oocyte fertilization (e.g., ICSI) using microtechniques for 10 or fewer oocytes. Do not report this code for conventional insemination.Report separately in addition to oocyte/embryo culture codes (89250, 89251, 89272).

Medical necessity for this procedure is established by the diagnosis of infertility and the patient's participation in an IVF cycle.

The lab analyst performs the technical steps to inseminate oocytes retrieved from a female patient during an in vitro fertilization (IVF) cycle.This involves introducing sperm into the oocyte to fertilize it.

IMPORTANT:For greater than 10 oocytes, use code 89281. Do not report 89281 in addition to 89280.This code does not include oocyte identification (89254), embryo preparation for transfer (89255), conventional insemination, assisted embryo hatching (89253), cryopreservation of embryo (89258), or biopsy of oocyte/embryo (89290, 89291). It should be reported separately, in addition to culture of oocyte(s)/embryo(s) codes (89250, 89251, 89272) when performed during the same cycle.

In simple words: This procedure helps fertilize eggs (oocytes) in a lab using specialized microscopic techniques. It is used for up to 10 eggs at a time to help with conception and pregnancy.

This code represents the laboratory services for assisted oocyte fertilization using microtechniques, specifically for 10 or fewer oocytes.The procedure involves highly sophisticated equipment and high power magnification to introduce a single sperm into a mature oocyte after stripping the outer layer. It is typically ordered in facilities specializing in reproductive medicine and infertility treatments.

Example 1: A 35-year-old female undergoing IVF has 8 oocytes retrieved.Intracytoplasmic sperm injection (ICSI) is performed, and code 89280 is reported., A couple experiencing infertility chooses IVF. The female has 10 oocytes retrieved, and ICSI is performed. Code 89280 is reported., A 40-year-old female undergoing IVF has 6 oocytes retrieved, and assisted oocyte fertilization using microtechniques is performed. Code 89280 is used for billing.

Documentation should include the number of oocytes fertilized using microtechniques, confirmation that the procedure was ICSI or other assisted fertilization and not conventional insemination, and any related procedures performed during the IVF cycle.

  • Specialties:Reproductive Endocrinology, Infertility
  • Place of Service:Office
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