In simple words: This lab test involves a tiny biopsy of cells from an egg or embryo to check for genetic problems before it's implanted in the uterus during in-vitro fertilization (IVF).

This CPT code encompasses the microscopic biopsy of up to five oocyte polar bodies or embryo blastomeres, utilizing a microtechnique, specifically for preimplantation genetic diagnosis (PGD).The procedure involves the aspiration and extraction of these cells for genetic analysis to screen for chromosomal abnormalities or genetic disorders before embryo implantation. This service does not include subsequent procedures such as embryo culture or preparation for transfer.

Example 1: A patient undergoes IVF, and several embryos are created.Prior to embryo transfer, a biopsy of one polar body from each of five embryos is performed for PGD to screen for aneuploidy., A couple with a known genetic condition opts for PGD to reduce the risk of transmitting the condition to their child.A biopsy of blastomeres is performed on three embryos created during an IVF cycle., During an IVF cycle, a patient chooses PGD to test for multiple genetic disorders. A polar body biopsy is performed on 5 embryos to assess for cystic fibrosis, Huntington's disease and other chromosomal abnormalities.

* Patient consent form for PGD.* Detailed clinical history including genetic testing results for the patient and their partner (if applicable).* IVF cycle documentation including date of oocyte retrieval, fertilization methods, and embryo development.* Microscopic images and pathology reports detailing the biopsy results.* Lab requisition forms indicating the specific genetic tests performed.

** This code is specific to the biopsy procedure itself and does not include other services such as genetic testing or embryo transfer.Ensure that these are billed separately using the appropriate CPT codes. Always cross-reference with payer-specific guidelines for accurate billing and reimbursement.