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2025 CPT code 89322

Semen analysis; volume, count, motility, and differential using strict morphologic criteria (e.g., Kruger).

Use 89322 when semen analysis is performed using strict morphologic criteria (e.g., Kruger or WHO). If less stringent criteria are used, other codes may be appropriate.Refer to current CPT coding guidelines for proper code selection.

Modifiers may be applicable to 89322. For example, modifier 91 is used for repeat laboratory tests, modifier 90 indicates the test was performed by an outside laboratory, and modifier 52 can indicate a reduced service.

Medical necessity for 89322 is established when evaluating male infertility, monitoring post-vasectomy status, or investigating potential infections or inflammation in the male reproductive tract.

The laboratory analyst performs the technical aspects of the semen analysis, including measuring volume, assessing sperm count, motility, and morphology using strict criteria. They also conduct a white blood cell differential.

IMPORTANT:Code 89331 (Sperm evaluation, for retrograde ejaculation, urine, sperm concentration, motility, and morphology, as indicated) may be reported in addition to 89322.

In simple words: This test analyzes a semen sample to check if a man might be having problems with fertility. The test looks at how much semen there is, how many sperm are present, how well the sperm move, and what percentage of the sperm look normal under a microscope. It also checks for signs of infection.

This code represents a comprehensive semen analysis evaluating volume, sperm count, motility, and a differential of white blood cells using strict morphologic criteria, such as the Kruger or WHO criteria.The analysis includes assessing sperm morphology, which evaluates the size and shape of the sperm head, the length of the tail, and other structural characteristics. It can be performed manually or with computer-assisted software. The report typically includes the results and normal reference ranges for each parameter. A white blood cell differential is also performed to detect potential inflammation or infection.

Example 1: A couple experiencing difficulty conceiving is referred for infertility testing. The male partner undergoes semen analysis using code 89322 to assess sperm health and identify potential male factor infertility., A man who has undergone a vasectomy has a semen analysis (89322) to confirm the absence of sperm and the success of the procedure., A man with a history of recurrent infections undergoes semen analysis (89322), including a white blood cell differential, to evaluate the presence of infection or inflammation in the reproductive tract.

Documentation should include the reason for the semen analysis (e.g., infertility evaluation, post-vasectomy confirmation), the date of the last ejaculation, and any relevant medical history that could affect sperm quality, such as recent illness, fever, or medication use. The report should detail the volume, sperm count, motility, morphology (using strict criteria), and white blood cell differential.

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