2025 CPT code 90375
(Active) Effective Date: N/A Revision Date: N/A Medicine - Immune Globulins, Serum or Recombinant Products Medicine Services and Procedures Feed
Human rabies immune globulin (RIG) for intramuscular and/or subcutaneous use.
Modifiers may apply depending on the circumstances of the service.Refer to the most recent CPT codebook for modifier usage guidelines.
Medical necessity for 90375 is established when a patient has a known or suspected exposure to rabies. This is often determined based on the type of animal, the nature of the exposure (bite, scratch, mucous membrane contact), and the animal's rabies status.
The physician or qualified healthcare professional administers the rabies immune globulin injection, ensuring proper technique and documentation.They should also counsel the patient regarding potential risks and benefits.
In simple words: This code is for a shot of rabies immune globulin (a medicine with antibodies that fight the rabies virus). The shot is given into a muscle or under the skin to help protect against rabies after someone has been exposed to the virus.
CPT code 90375 represents the administration of human rabies immune globulin (RIG) for intramuscular and/or subcutaneous injection.This procedure involves the injection of a preparation containing antibodies against the rabies virus, providing passive immunity to protect against or treat rabies exposure.The specific dosage and route of administration (intramuscular or subcutaneous) should be documented. Note that a separate code (90376) exists for heat-treated RIG.
Example 1: A patient presents to the emergency department after a bat bite. The physician administers 90375 (Rabies Immune Globulin) along with the rabies vaccine (90675/90676) as per the rabies post-exposure prophylaxis guidelines., A person who is at high risk for rabies exposure (e.g., wildlife handler, laboratory worker) may receive a prophylactic dose of rabies immune globulin prior to exposure., During a wilderness expedition, a person is bitten by a potentially rabid animal.A healthcare provider in the field might administer the rabies immune globulin (90375) as a first-line treatment prior to more comprehensive medical care.
** Always verify the specific product used (heat-treated or not) to ensure the correct code is selected.Incorrect code selection could impact reimbursement.
- Revenue Code: P6D (Minor Procedures - Other)
- RVU: This information varies by payer and location.Consult payer-specific fee schedules for current RVUs and reimbursement rates.
- Global Days : No global period applies to this code.
- Payment Status: Active
- Modifier TC rule: No TC modifier applies to this code.
- Fee Schedule : Fee schedules vary widely depending on the payer, location, and year.Contact payers or refer to historical fee schedule databases for specifics.
- Specialties:Infectious Disease, Emergency Medicine, Public Health
- Place of Service:Office, Emergency Room - Hospital, Inpatient Hospital, Other Place of Service