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BETA v.3.0

2025 CPT code 90740

Hepatitis B vaccine (HepB), dialysis or immunosuppressed patient dosage, 3 dose schedule, for intramuscular use

This code identifies only the vaccine product. Administration codes (90460, 90461, 90471-90474) must be reported separately. Do not report with SARS-CoV-2 administration codes (90480) unless both a SARS-CoV-2 vaccine and 90740 are administered at the same encounter.

Modifier 51 is not applicable.

Medical necessity for this code is established by the patient's condition (dialysis or immunosuppression) which places them at higher risk of hepatitis B infection and complications.

In simple words: This code covers the hepatitis B vaccine given in the muscle to protect people with weakened immune systems or those on dialysis. It requires three shots.

This code represents the supply of a hepatitis B vaccine specifically designed for patients undergoing dialysis or who are immunosuppressed. It is administered intramuscularly and follows a three-dose schedule.

Example 1: A 55-year-old patient with end-stage renal disease receiving hemodialysis requires hepatitis B vaccination. 90740 is reported for the vaccine supply, along with the appropriate administration code., A 30-year-old patient with HIV, an immunosuppressive condition, is scheduled for a hepatitis B vaccination. 90740 is reported for each vaccine dose supplied, and a separate administration code is also reported., A 60-year-old patient receiving chemotherapy, which causes immunosuppression, receives the hepatitis B vaccine. Code 90740 is reported for the vaccine, along with an administration code.

Documentation should support the patient's dialysis or immunosuppressed status, the dosage and date of administration of each dose, and the manufacturer of the vaccine.

** This vaccine is typically given in a 0, 1, and 6-month schedule. For detailed information on dosage and administration, consult the manufacturer's package insert.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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