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2025 CPT code 93463

Pharmacologic agent administration (e.g., inhaled nitric oxide, intravenous infusion of nitroprusside, dobutamine, milrinone, or other agent) including assessing hemodynamic measurements before, during, after, and repeat pharmacologic agent administration, when performed.

Code 93463 is an add-on code and should be reported only once per heart catheterization procedure. It is to be used in conjunction with a primary code for diagnostic heart catheterization (e.g., 93451-93453, 93456-93461). Do not report this code for pharmacologic agent administration for procedures such as stress testing, right ventricular biopsy, or during electrophysiology studies.

Modifiers may be applicable to 93463 to indicate specific circumstances of the procedure, such as reduced services (modifier 52), or discontinued procedures (modifiers 73 or 74) if applicable.

Medical necessity for 93463 must be supported by documentation indicating the clinical rationale for administering the pharmacologic agent during cardiac catheterization. This may include evaluating the patient's response to treatment for conditions such as heart failure or pulmonary hypertension, or assessing the need for further intervention.

The physician is responsible for administering the pharmacologic agent, monitoring hemodynamic measurements, and interpreting the patient's response. They must also document the medical necessity of the procedure and the specific agent used.

In simple words: During a heart catheterization procedure, the doctor gives you medicine through an IV or by inhalation to see how your heart reacts.They'll monitor your heart's function before, during, and after giving the medicine, and may give you more doses if needed. This helps them understand how well your heart is working.

This code describes the administration of a pharmacological agent, such as inhaled nitric oxide or an intravenous infusion of nitroprusside, dobutamine, milrinone, or other inotropic agents during cardiac catheterization. It includes assessing hemodynamic measurements before, during, and after administration, and potential repeat administrations of the agent as needed. The code is used for evaluating hemodynamic response to the medication, and should be reported in addition to the primary procedure code for the catheterization. It is not to be used with interventional heart catheterization procedures, intracoronary assessment of pressure/flow/resistance, or intracoronary imaging.

Example 1: A patient with congestive heart failure undergoes right heart catheterization, and nitric oxide is administered to assess the patient’s response to pulmonary vasodilation., During left heart catheterization, a patient receives dobutamine to evaluate the heart’s contractility and response to inotropic support., A patient undergoing combined right and left heart catheterization receives milrinone, and hemodynamic measurements are taken before, during, and after administration to assess the effect on cardiac output and pulmonary artery pressure.

Documentation should include the specific pharmacologic agent used, dosage, route of administration, the reason for administration, hemodynamic measurements obtained before, during, and after administration, and the patient’s response to the agent. The medical necessity of the procedure should also be clearly documented.

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