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2025 HCPCS code J3355

Urofollitropin injection, 75 IU

This code represents only the drug itself, not the administration. Check with individual payers to determine if the administration can be billed separately. Also, verify if there are any specific coding guidelines or requirements from the payer.

Modifiers may be applicable depending on the specific circumstances of the administration. Consult modifier guidelines to ensure correct usage.

Medical necessity must be established for the use of urofollitropin. It is typically indicated for infertility treatment in women with FSH deficiency or other conditions where ovarian stimulation is needed. Payer policies may vary regarding coverage criteria.

In simple words: This injection contains a hormone called urofollitropin, which helps women who are having trouble getting pregnant. It works by helping the ovaries produce eggs. Each injection contains 75 IU of the hormone and is given just under the skin.

Urofollitropin is a purified version of a follicle stimulating hormone (FSH) used to treat infertility in women, particularly those with an FSH deficiency. This code represents one unit of 75 international units (IU) of urofollitropin administered subcutaneously.

Example 1: A 32-year-old woman with a diagnosed FSH deficiency receives a 75 IU dose of urofollitropin (J3355) subcutaneously as part of her infertility treatment., A woman undergoing in vitro fertilization (IVF) is prescribed daily injections of J3355 to stimulate egg production before egg retrieval., A patient receives J3355 in conjunction with other fertility medications to increase her chances of conception.

Documentation should include the diagnosis of infertility, the dosage administered (75 IU), the route of administration (subcutaneous), and medical necessity for the use of urofollitropin. Supporting documentation such as prior lab results indicating FSH deficiency and treatment plan should also be included.

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