2025 HCPCS code S3645
(Active) Effective Date: N/A Revision Date: N/A Laboratory Testing - HIV-1 antibody testing Miscellaneous Provider Services and Supplies Feed
HIV-1 antibody testing of oral mucosal transudate.
Modifiers may apply depending on the circumstances of service. Consult your payer's specific guidelines.
Medical necessity is established by the presence of symptoms suggestive of HIV, risk factors for HIV exposure, or the patient's request for testing.
The provider collects the oral mucosal transudate sample using an oral pad and performs the HIV-1 antibody test. Interpretation of the results and further clinical management is also the responsibility of the provider.
In simple words: This code is for a test that checks for HIV antibodies in fluid from a person's mouth. A special pad collects the fluid, which is then tested.The test shows if someone has been exposed to HIV.
This HCPCS code, S3645, represents the testing of oral mucosal transudate (fluid from the mouth) to detect the presence of HIV-1 antibodies.The procedure involves collecting a sample using an oral pad, which is then analyzed for the presence of antibodies.A positive result indicates prior exposure to the HIV-1 virus.
Example 1: A patient presents to a clinic with symptoms suggestive of HIV infection. The provider orders an HIV-1 antibody test using oral mucosal transudate as a less invasive alternative to blood testing.S3645 is used to bill for this test., During a routine check-up, a patient expresses concern about potential HIV exposure. The provider orders an HIV-1 antibody test via oral fluid sample for faster and easier testing experience.S3645 is billed for this service., A patient participates in a research study investigating alternative methods for HIV screening.An oral mucosal transudate sample is collected, and S3645 is used for billing purposes in relation to the research project, if applicable.
* Patient demographics and identifying information.* Clinical indication for the test (reason for ordering).* Date and time of the procedure.* Method of sample collection (oral pad).* Test results (positive or negative).* Provider's interpretation and clinical management plan.
** This code is not reimbursable by Medicare.It's primarily used by private payers and Medicaid. The code includes all components of the procedure, unlike CPT codes which require separate billing for each component.
- Payment Status: Not payable by Medicare
- Specialties:Infectious Disease, Internal Medicine, Family Medicine
- Place of Service:Office, Clinic, Urgent Care Facility