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2025 HCPCS code S5521

All supplies (including catheter) necessary for insertion of a midline venous catheter for home infusion therapy.

Use this code only for the supplies associated with midline catheter insertion for home infusion therapy.Do not use this code for supplies associated with other types of catheters or infusion therapies.

Medical necessity for home infusion therapy and the use of a midline catheter must be established.This includes documentation supporting the patient's clinical condition, the need for intravenous therapy, and the appropriateness of home administration.

Home infusion therapy typically involves a nurse or other skilled professional who inserts the midline catheter and manages the infusion process.

IMPORTANT:For the nursing services associated with the insertion, use S5523. Do not report both S5521 and S5523 for the same midline catheter insertion.

In simple words: This code covers the cost of all the supplies needed to put in a midline catheter for home infusion therapy. This type of catheter is used to deliver medications or fluids at home for a few weeks.

This code represents all supplies (including the catheter) required for insertion of a midline venous catheter for home infusion therapy.A midline catheter is used for medium-term infusion therapy, typically lasting one to eight weeks.

Example 1: A patient receiving long-term antibiotic therapy requires a midline catheter for administration at home., A patient undergoing chemotherapy requires a midline catheter for home administration of medications., A patient with a chronic illness needs regular intravenous medications, and a midline catheter is placed for ease of access and administration in a home setting.

Documentation should include the type and size of the midline catheter inserted, the date of insertion, and the site of insertion. The medical necessity for home infusion therapy and the use of a midline catheter should also be documented.

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