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2025 ICD-10-CM code A31.2

Disseminated Mycobacterium avium-intracellulare complex (DMAC).

Use additional code to identify resistance to antimicrobial drugs (Z16.-). Exclude certain localized infections - see body system-related chapters. Exclude carrier or suspected carrier of infectious disease (Z22.-), infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-), infectious and parasitic diseases specific to the perinatal period (P35-P39), influenza and other acute respiratory infections (J00-J22).

Medical necessity for DMAC treatment is established by confirming the diagnosis through positive blood cultures or other appropriate diagnostic testing in a patient with compatible symptoms and a known risk factor like immunosuppression.Prophylaxis may be medically necessary for high-risk individuals.

Physicians diagnosing and managing DMAC should consider patient's immune status, particularly HIV status. Conduct thorough history and physical exam, focusing on symptoms like fever, weight loss, and respiratory issues. Order laboratory tests including blood cultures, complete blood count (CBC), liver function tests, and potentially an HIV test. Imaging studies may be necessary based on the patient's presentation. Treatment involves prolonged antimicrobial therapy with two or three drugs for at least 12 months.

In simple words: DMAC is an infection throughout the body caused by bacteria found in water, soil, and dust. It mainly affects people with weakened immune systems, like those with advanced HIV/AIDS.Symptoms can include fever, weight loss, night sweats, stomach pain, and tiredness.

Disseminated infection caused by Mycobacterium avium complex (MAC), consisting of Mycobacterium avium and Mycobacterium intracellulare.It typically affects individuals with compromised immune systems, particularly those with advanced HIV infection. Symptoms include fever, weight loss, night sweats, abdominal pain, shortness of breath, fatigue, diarrhea.

Example 1: A patient with advanced HIV and a CD4 count below 50 presents with fever, night sweats, weight loss, and diarrhea. Blood cultures confirm DMAC., A patient with a history of solid organ transplant develops persistent fever, fatigue, and abdominal pain.After ruling out other causes, DMAC is diagnosed via blood culture., A patient on long-term corticosteroid therapy for an autoimmune disorder presents with respiratory symptoms and general malaise. Imaging and cultures reveal DMAC infection.

Documentation should include evidence of immunosuppression (e.g., HIV test results, transplant history, chronic corticosteroid use), presenting symptoms, laboratory results (blood cultures, CBC, liver function tests), and imaging findings. Details of antimicrobial therapy and treatment duration should also be documented.

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