In simple words: Sepsis is a serious medical condition where the body overreacts to an infection in the bloodstream.This code indicates the infection is caused by a type of bacteria called "gram-negative," but the exact kind isn't known.This can cause fever, low blood pressure, and breathing problems, among other symptoms.

Sepsis due to unspecified gram-negative organisms. This condition involves a severe systemic inflammatory response to an infection by gram-negative bacteria. The specific type of gram-negative bacteria is not documented.

Example 1: A patient presents with fever, hypotension, and tachycardia. Blood cultures reveal the presence of gram-negative bacteria, but the specific type is not identified. The patient is diagnosed with sepsis due to unspecified gram-negative organisms (A41.50)., A post-surgical patient develops signs of infection, including fever and elevated white blood cell count. Cultures identify gram-negative bacteria, but further specification is unavailable. A41.50 is used to code the sepsis., An elderly patient with a urinary tract infection develops confusion, rapid breathing, and low blood pressure.Cultures show gram-negative bacteria, but the lab is unable to determine the species. The physician diagnoses sepsis due to unspecified gram-negative bacteria (A41.50).

Documentation should include signs and symptoms of sepsis (e.g., fever, hypotension, tachycardia, tachypnea, altered mental status), laboratory results (positive blood cultures with gram-negative organisms), and any other relevant clinical findings.