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2025 ICD-10-CM code A41.52

Sepsis due to Pseudomonas.

Use additional code to identify resistance to antimicrobial drugs (Z16.-). Do not code for sepsis if the infection is localized. Code first any underlying conditions or complications.

Medical necessity for treatment of Pseudomonas sepsis is established by the presence of clinical signs and symptoms of sepsis along with positive cultures for Pseudomonas aeruginosa.The severity of the sepsis and the patient's overall condition further support the medical necessity of treatment.

Clinicians should suspect pseudomonal sepsis in immunocompromised patients, critically ill individuals, and those with comorbidities or multiple hospitalizations. Treatment may include antibiotics, intravenous fluids, oxygen, and sometimes surgery to remove infected tissue.

In simple words: Sepsis due to Pseudomonas is a serious infection where the body overreacts to harmful substances produced by Pseudomonas bacteria in the blood. It usually affects people who have been in the hospital for a while and can be very dangerous.

Sepsis due to Pseudomonas aeruginosa. This condition involves a systemic inflammatory response to toxins released by Pseudomonas bacteria in the bloodstream. It's often seen in hospitalized patients and can be life-threatening.

Example 1: A patient with a compromised immune system develops fever, low blood pressure, and difficulty breathing after a prolonged hospital stay. Blood cultures reveal Pseudomonas aeruginosa, indicating sepsis., A patient with severe burns develops a bloodstream infection with Pseudomonas aeruginosa, leading to sepsis and requiring aggressive antibiotic treatment., An infant with agammaglobulinemia presents with ecthyma gangrenosum and systemic symptoms. Cultures confirm Pseudomonas aeruginosa as the cause of sepsis.

Documentation should include the type of infection, causative agent (Pseudomonas aeruginosa), evidence of systemic inflammatory response syndrome (SIRS), and any associated organ dysfunction.

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