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2025 ICD-10-CM code A49.01

Methicillin-susceptible Staphylococcus aureus (MSSA) infection at an unspecified site.

Use this code only when the site of the MSSA infection is unspecified. If the site is known, a more specific code should be used.

Medical necessity for treatment is established by the presence of a clinically significant MSSA infection, impacting the patient's health and requiring medical intervention.

Physicians typically diagnose MSSA based on symptoms, physical examination, and laboratory tests like blood cultures or cultures from the infected site. Treatment includes antibiotics, wound care, and supportive measures.

In simple words: MSSA is a bacterial infection treatable with common antibiotics. This particular code is used when the location of the infection isn't specified by the doctor.

Methicillin-susceptible Staphylococcus aureus (MSSA) infection refers to an infection caused by a strain of Staphylococcus aureus bacteria that is still susceptible to methicillin and other beta-lactam antibiotics. This condition can manifest in various parts of the body, and this code specifically denotes an infection where the site is not specified.

Example 1: A patient presents with fever, chills, and general malaise. Blood cultures reveal MSSA, but there is no clear source of infection., A patient with a recent surgical wound develops signs of infection. Cultures identify MSSA as the causative agent., An infant experiences fever and widespread skin peeling. Cultures confirm MSSA, leading to a diagnosis of staphylococcal scalded skin syndrome.

Documentation should include evidence of the MSSA infection, such as positive cultures, along with clinical findings supporting the diagnosis. If the site of infection is known, a more specific code should be used.

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