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2025 ICD-10-CM code A51.44

Secondary syphilitic nephritis. This is a kidney condition that occurs during the second stage of syphilis.

Use additional code to identify resistance to antimicrobial drugs (Z16.-). Certain localized infections are excluded (see body system-related chapters). Carrier or suspected carrier of infectious disease is excluded (Z22.-), as are infectious and parasitic diseases complicating pregnancy, childbirth, and the puerperium (O98.-) and infectious and parasitic diseases specific to the perinatal period (P35-P39).

Medical necessity is established by the diagnosis of secondary syphilitic nephritis, supported by clinical findings and laboratory results.Treatment is necessary to prevent further kidney damage and other complications of syphilis.

The provider diagnoses the condition based on the patient’s history, physical examination, blood tests, suspected lesions, and body fluid tests. Serologic tests for syphilis and dark field microscopy are classic tests to diagnose this condition. Treatment includes intramuscular injections of the antibiotic penicillin; those allergic to penicillin may be prescribed doxycycline, tetracycline, or ceftriaxone. Intravenous (IV) electrolytes are administered and dialysis is indicated in severe cases.

In simple words: Secondary syphilitic nephritis is a kidney problem that happens in the second stage of syphilis, a sexually transmitted infection.It happens when the infection spreads from the initial sores to the kidneys.

Secondary syphilitic nephritis is a manifestation of the second stage of syphilis that affects the kidney after the spread of the pathogen from primary lesions. Syphilis is a sexually transmitted disease caused by the bacterium Treponema pallidum.

Example 1: A patient presents with lower abdominal pain, burning sensation during urination, cloudy urine, edema, and glomerulonephritis, along with typical syphilis symptoms.Tests confirm secondary syphilitic nephritis., A pregnant woman with secondary syphilis develops kidney problems, indicating secondary syphilitic nephritis.This requires careful management to protect both the mother and the fetus., A patient being treated for primary syphilis develops proteinuria and other signs of kidney dysfunction.This suggests the progression to secondary syphilitic nephritis.

Documentation should include evidence of secondary syphilis, such as positive serological tests and characteristic lesions, as well as documentation of nephritis, including laboratory findings and clinical symptoms like proteinuria, hematuria, and edema. The type, location, and stage of syphilis should be documented.

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