In simple words: Hyperkeratosis of yaws is a skin problem caused by a bacterial infection called yaws. It causes thick, painful sores on the palms of the hands and soles of the feet. This can make it hard to walk. Yaws is common in children living in warm, tropical areas with poor hygiene.

Hyperkeratosis of yaws is a skin manifestation of yaws, a chronic infectious disease caused by the bacterium Treponema pallidum subspecies pertenue. It is characterized by the development of multiple thick, painful, papillomatous lesions on the palms of the hands and soles of the feet, sometimes leading to a crab-like gait. This condition typically occurs in the primary or secondary stages of yaws. Diagnosis is based on clinical presentation, exposure history, and laboratory tests like dark-field microscopy.

Example 1: A 10-year-old child living in a rural tropical area presents with painful, thick lesions on the soles of their feet, making it difficult to walk.Upon examination, multiple papillomatous lesions are observed, and a history of playing in contaminated soil is noted. Dark-field microscopy confirms the presence of Treponema pallidum subspecies pertenue, leading to a diagnosis of hyperkeratosis of yaws., A group of children living in a community with limited access to clean water and sanitation develop skin lesions. Several children exhibit hyperkeratotic lesions on their palms and soles, consistent with yaws. Public health officials initiate a campaign to improve hygiene practices and provide antibiotic treatment to affected children., A traveler returning from a tropical region develops painful lesions on their hands.A dermatologist identifies the lesions as characteristic of yaws and prescribes appropriate antibiotic therapy.

Documentation should include the location and characteristics of the skin lesions, patient's travel history, living conditions, and any relevant laboratory findings (e.g., dark-field microscopy).