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BETA v.3.0

2025 ICD-10-CM code B00.3

Herpesviral meningitis. This is an inflammation of the meninges (membranes surrounding the brain and spinal cord) caused by the herpes simplex virus.

Use additional code to identify resistance to antimicrobial drugs (Z16.-). Excludes1: congenital herpesviral infections (P35.2). Excludes2: anogenital herpesviral infection (A60.-) gammaherpesviral mononucleosis (B27.0-) herpangina (B08.5).

Medical necessity for treatment of herpesviral meningitis is established by the presence of clinical signs and symptoms, confirmed by laboratory testing and imaging studies. Treatment aims to reduce the severity and duration of symptoms, prevent complications like seizures and hydrocephalus, and improve patient outcomes.

Clinicians diagnose herpesviral meningitis based on patient history, physical and neurological examinations, imaging studies (CT, MRI, cerebral angiography, EEG), and laboratory tests like PCR of cerebrospinal fluid. Treatment typically involves antiviral medications like acyclovir to reduce brain swelling and prevent seizures.

In simple words: Herpesviral meningitis is a brain infection caused by the herpes virus. It can cause symptoms like fever, headache, stiff neck, and sensitivity to light. In severe cases, it can lead to seizures or other complications.

Herpesviral meningitis is an inflammation of the meninges, the protective membranes surrounding the brain and spinal cord, caused by the herpes simplex virus (HSV). This infection can manifest as fever, severe headache, neck stiffness, light sensitivity, nausea, vomiting, sleepiness, reduced appetite, delirium, and lethargy. Severe cases can lead to seizures, hydrocephalus (fluid buildup in the brain), or mental retardation.

Example 1: A 25-year-old female presents with fever, severe headache, stiff neck, and sensitivity to light. PCR of cerebrospinal fluid confirms herpesviral meningitis., A newborn infant develops fever, lethargy, and poor feeding. Testing reveals herpesviral meningitis transmitted from the mother during delivery., A 40-year-old male with a history of recurrent herpes experiences fever, headache, and seizures. Imaging studies and CSF analysis confirm herpesviral meningitis.

Documentation should include patient history, physical and neurological exam findings, results of imaging studies (CT, MRI, cerebral angiography, EEG), and laboratory tests, including PCR of cerebrospinal fluid. Details of treatment with antiviral medications should also be documented.

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