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2025 ICD-10-CM code B00.7

Disseminated herpesviral disease. This condition involves the spread of herpesvirus through the bloodstream to multiple organs, predominantly affecting immunocompromised individuals.

Use additional codes to identify any underlying conditions contributing to the immunocompromised state.

Medical necessity is established by the presence of clinical findings consistent with disseminated herpesviral disease in an immunocompromised individual, confirmed by appropriate diagnostic testing.

Physicians diagnose disseminated herpesviral disease based on patient history, physical examination, blood tests, viral culture, and PCR. Treatment involves oral antiviral medications (acyclovir, valacyclovir, famciclovir), topical antivirals, pain relievers, and management of complications.

In simple words: Disseminated herpesviral disease is a serious infection caused by the herpes virus, occurring mostly in people with weakened immune systems. The virus spreads through the bloodstream, affecting different organs and causing sores, fever, and other symptoms. It can sometimes lead to brain inflammation.

Disseminated herpesviral disease is a severe manifestation of herpesviral infection that occurs primarily in individuals with weakened immune systems. It is characterized by the spread of the virus through the bloodstream to various organs. Symptoms include vesicular or ulcerative lesions at multiple sites, fever, weakness, muscle aches, localized swelling, and enlarged lymph nodes. In severe cases, it can lead to meningitis or encephalitis.

Example 1: An immunocompromised patient presents with fever, weakness, and widespread vesicular lesions. Blood tests and PCR confirm disseminated herpesviral infection., A patient with HIV develops herpesviral encephalitis, exhibiting neurological symptoms and confirmed through cerebrospinal fluid analysis., A transplant recipient experiences multi-organ involvement due to disseminated herpesviral disease, requiring intensive antiviral therapy and supportive care.

Documentation should include evidence of immunocompromised status, clinical presentation (lesions, fever, other symptoms), laboratory results (blood tests, viral culture, PCR), and treatment details.

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