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2025 ICD-10-CM code B00.82

Herpes simplex myelitis is a rare manifestation of herpes infection affecting the spinal cord, typically seen in immunocompromised individuals.

Use additional code to identify resistance to antimicrobial drugs (Z16.-). This code excludes certain localized infections (see body system-related chapters), carrier or suspected carrier of infectious disease (Z22.-), infectious and parasitic diseases complicating pregnancy, childbirth, and the puerperium (O98.-), and infectious and parasitic diseases specific to the perinatal period (P35-P39).

Medical necessity for treatment of herpes simplex myelitis is established by the confirmed presence of HSV infection in the spinal cord causing symptoms such as weakness, numbness, pain, and functional impairment. Treatment aims to control the infection, reduce inflammation, and manage symptoms.

Diagnosis involves patient history, neurological examination, MRI of the spine, and laboratory tests of blood and cerebrospinal fluid (CSF), including PCR. Treatment typically includes antiviral medication like acyclovir and supportive care.

In simple words: Herpes simplex myelitis is a rare but serious complication of herpes that causes inflammation of the spinal cord. It can cause weakness, numbness, pain, and difficulty walking, mainly in the legs and lower body.It's more common in people with weakened immune systems.

Herpes simplex myelitis is inflammation of the spinal cord caused by the herpes simplex virus (HSV). It is a rare condition that typically affects individuals with weakened immune systems. Symptoms may include lower limb weakness or numbness, back pain, difficulty walking, and urinary abnormalities. In severe cases, it can lead to paraplegia.

Example 1: An immunocompromised patient presents with progressive lower limb weakness, numbness, and back pain. MRI reveals inflammation in the spinal cord, and CSF analysis confirms the presence of HSV, leading to a diagnosis of herpes simplex myelitis., A patient with a history of herpes experiences sudden difficulty walking and urinary retention. After ruling out other causes, a diagnosis of herpes simplex myelitis is made based on positive HSV PCR in CSF., A patient undergoing chemotherapy develops numbness and tingling in their legs. Imaging and laboratory testing reveal herpes simplex myelitis as the cause, requiring antiviral treatment and supportive care.

Documentation should include details of the patient's symptoms, neurological examination findings, imaging results (MRI of the spine), and laboratory results (blood and CSF analysis, including PCR for HSV). Medical history, including any immunosuppressive conditions or prior herpes infections, should also be documented.

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