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BETA v.3.0

2025 ICD-10-CM code B39.9

Histoplasmosis, unspecified.

Use additional codes to specify any associated conditions (e.g., meningitis, pericarditis) and any identified resistance to antimicrobial drugs (Z16.-).

Medical necessity depends on the severity and manifestation of histoplasmosis. Testing and treatment are medically necessary for symptomatic individuals, particularly those with compromised immune systems or disseminated disease.

Clinicians should evaluate patients for respiratory symptoms, obtain a thorough history including potential exposure to bird or bat droppings, and conduct necessary diagnostic tests (e.g., blood and urine tests, antibody tests, sputum culture, chest X-ray, CT scan, biopsy). Treatment with antifungal medications may be necessary for severe infections.

In simple words: Histoplasmosis is an infection you get by breathing in a fungus found in bird and bat droppings. It usually affects the lungs. This particular code means the doctor hasn't specified what kind of histoplasmosis it is.

Histoplasmosis is a fungal infection caused by inhaling spores of the fungus *Histoplasma capsulatum*. It primarily affects the lungs but can sometimes spread to other organs (disseminated histoplasmosis). This code specifies histoplasmosis without further details about its type or manifestation.

Example 1: A patient presents with fever, cough, and fatigue after cleaning out an old chicken coop. Diagnostic tests confirm histoplasmosis, but the specific type is not determined. B39.9 is used., An immunocompromised individual develops disseminated histoplasmosis with multiple organ involvement, but the initial site of infection is unknown. B39.9 is appropriate until further details emerge., A patient with a history of exploring caves develops respiratory symptoms consistent with histoplasmosis. Initial testing does not specify the type, so B39.9 is used.

Documentation should include patient history (including potential exposures), physical exam findings, diagnostic test results (e.g., cultures, imaging, serology), and treatment plan.

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