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BETA v.3.0

2025 ICD-10-CM code B57.1

Acute Chagas disease without heart involvement.

Use additional code to identify resistance to antimicrobial drugs (Z16.-).Do not use this code for Chagas disease with heart involvement (B57.2) or chronic Chagas disease (B57.3).

Medical necessity for treatment of acute Chagas disease is established by the confirmation of the infection and the presence of clinical symptoms or evidence of the parasite.Early diagnosis and treatment are crucial to prevent the development of chronic Chagas disease, which can have serious long-term health consequences, including heart disease.

The provider diagnoses the condition based on history of exposure, physical examination, and symptoms. Laboratory tests include microscopic examination of blood, serologic tests for antibody detection, and polymerase chain reaction (PCR). Treatment consists of antiprotozoal drugs such as benznidazole and nifurtimox.

In simple words: Acute Chagas disease is an infection spread by the "kissing bug," or through blood transfusions or from mother to baby at birth. This code signifies the early stage of the disease without any heart problems.

Acute Chagas disease without heart involvement refers to an infectious disease, abrupt in onset or having a short course, caused by the parasite Trypanosoma cruzi.It's typically transmitted by the bite of blood-sucking insects (kissing bugs), direct entry through the mucosa or cuts in the skin, during blood transfusions or organ transplants, or by an infected mother to her newborn.This condition occurs without any associated cardiac complications.

Example 1: A patient presents with fever, headache, and enlarged lymph nodes after a recent trip to South America where they were bitten by insects. Blood tests confirm acute Chagas disease without cardiac involvement., A newborn infant tests positive for Trypanosoma cruzi, contracted from their infected mother during childbirth. The infant shows no signs of heart complications, indicating acute Chagas disease without heart involvement., A patient develops fever and swelling at the site of a cut after handling raw meat contaminated with Trypanosoma cruzi. Subsequent tests reveal acute Chagas disease, with no cardiac involvement detected.

Documentation should include history of exposure, physical exam findings (e.g., swelling, fever, enlarged lymph nodes), and laboratory results confirming the presence of Trypanosoma cruzi and absence of cardiac complications.Details about potential exposure routes, like insect bites, travel history, blood transfusions, or maternal infection, should also be documented.

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