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BETA v.3.0

2025 ICD-10-CM code C44.521

Squamous cell carcinoma of the skin of the breast.

Use additional codes to identify any associated functional activity (Chapter 4) or any contributing factors.

Medical necessity is established by the presence of a confirmed diagnosis of squamous cell carcinoma of the skin of the breast. The chosen treatment should be appropriate for the stage and characteristics of the cancer.

A patient with squamous cell carcinoma of the skin of the breast may present with small, hard nodules or a flat, non-healing sore that may ulcerate, bleed, and form scabs. The carcinoma can spread to nearby lymph nodes and invade surrounding tissues. Diagnosis involves physical examination, biopsy, and imaging studies like CT and/or MRI. Treatment options include surgical excision, chemotherapy, radiation therapy, cryotherapy, and photodynamic therapy.

In simple words: Squamous cell carcinoma is a type of skin cancer that can develop on the breast. It's caused by abnormal skin cells growing out of control.People who get a lot of sun or have been exposed to certain chemicals are more likely to develop this type of skin cancer.

Squamous cell carcinoma (SCC) of the skin of the breast arises from the uncontrolled multiplication of malignant cells derived from the epithelium (the outer layer of skin) or exhibiting squamous cell differentiation. SCC is more prevalent in individuals with excessive exposure to sunlight or certain chemicals.

Example 1: A 65-year-old male patient with a history of sun exposure presents with a non-healing sore on the skin of his right breast. A biopsy confirms squamous cell carcinoma., A 50-year-old female patient presents with a small, hard nodule on the skin of her left breast. After imaging and biopsy, she is diagnosed with squamous cell carcinoma., A 70-year-old female patient with a history of chemical exposure presents with multiple lesions on the skin of her chest, including one on the breast. Biopsy confirms squamous cell carcinoma in multiple locations, including the breast.

Documentation should include details of the lesion (size, location, appearance), biopsy results, imaging findings (if any), treatment plan, and any relevant patient history (e.g., sun exposure, chemical exposure).

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